The impact of intestinal microbiota on bio-medical research: definitions, techniques and physiology of a “new frontier”

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Andrea Ticinesi
Antonio Nouvenne
Claudio Tana
Beatrice Prati
Nicoletta Cerundolo
Chiara Miraglia
Gian Luigi de' Angelis
Francesco Di Mario
Tiziana Meschi

Keywords

microbiome, dysbiosis, metagenomics, aging, nutrition, exercise

Abstract

In recent years the metagenomics techniques have allowed to study composition and function of the intestinal microbiota. The microbiota is a new frontier of biomedical research to be explored and there is growing evidence of its fundamental health-promoting activity. The present review gives a synthetic overview on the characteristics and the role of the microbiota in the adult with particular reference to physiology, pathophysiology and relationships with the host and the environment.

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