Acute eosinophilic pneumonia associated with glyphosate-surfactant exposure

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Wanda M. de Raadt
Petal A. Wijnen
Aalt Bast
Otto Bekers
Marjolein Drent

Keywords

Eosinophilic pneumonia after surfactant exposure

Abstract

We report a case of a female patient who developed acute eosinophilic pneumonia (AEP) after recent onset of smoking and exposure to glyphosate-surfactant.

The additional exposure associated with the recent start of smoking may have contributed to the development and/or severity of AEP.

A clinical relapse after re-challenge four years later both with smoking and glyphosate-surfactant made the association highly likely.

Respiratory distress is a factor of poor outcome and mortality after ingestion of glyphosate-surfactant.

This case highlights the importance of a thorough exposure history e.g., possible occupational and environmental exposures together with drug-intake.

Genotyping should be considered in cases of severe unexplained pulmonary damage

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