Wunderlich syndrome: a rare case in a young woman

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Maria Teresa Paparella
Laura Eusebi
Ilaria Gangai
Francesco Bartelli
Giuseppe Guglielmi


Wunderlich syndrome, Angiomyolipoma, Hemorrhage, Kidney


We report the case of a 29-year-old woman with Wunderlich syndrome, a rare spontaneous renal hemorrhage into the subcapsular and perinephric space. She presented to our emergency department with a sudden and persistent right flank pain in the abscence of abdominal injury. The onset of the symptoms can be insidious and lead to hypovolemic shock. Computed Tomography helps both in the diagnosis, detecting the renal hemorrhage, and contributes to an optimal patient management. Selective arterial embolisation is an efficient technique to stop acute and potential life-threatening hemorrhage and preserve the renal parenchyma.


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1. Katabathina VS, Katre R, Prasad SR, Surabhi VR, Shanbhogue AK, Sunnapwar A. Wunderlich syndrome: cross-sectional imaging review. J Comput Assist Tomogr. 2011 Jul-Aug;35(4):425-33.
2. Wang BH, Pureza V, Wang H. A tale of Wünderlich syndrome. J Surg Case Rep. 2012 Dec 4;2012(11):rjs015.
3. Albi G, Del Campo L, Tagarro D. Wunderlich’s syndrome: causes, diagnosis and radiological management. Clin Radiol 2002;57:840–5.
4. Medda M, Picozzi SC, Bozzini G, Carmignani L. Wunderlich's syndrome and hemorrhagic shock. J Emerg Trauma Shock. 2009 Sep;2(3):203-5.
5. Daliakopoulos SI. Spontaneous retroperitoneal hematoma: a rare devastating clinical entity of a pleiada of less common origins. Journal of Surgical Technique and Case Report. 2011 Jan;3(1):8-9.
6. Zhang JQ, Fielding JR, Zou KH. Etiology of spontaneous perirenal hemorrhage: a meta-analysis. J Urol. 2002 Apr;167(4):1593-6.
7. Kane D, Abdelrahman M, Looney AT, Eogan M. Wunderlich's syndrome in pregnancy: a shocking triad. BMJ Case Rep. 2019 May 19;12(5):e229219.
8. Lopes Vendrami C, Parada Villavicencio C, DeJulio TJ et al. Differentiation of Solid Renal Tumors with Multiparametric MR Imaging. Radiographics. 2017 Nov-Dec;37(7):2026-2042.
9. Baishya RK, Dhawan DR, Sabnis R. Spontaneous subcapsular renal hematoma: a case report and review of literature. Urol Ann. 2011;3: 44-46.
10. Timmermans LG. Stratégie thérapeutique du syndrome de Wunderlich [Therapeutic strategy for Wunderlich syndrome]. Acta Urol Belg. 1997 Oct;65(3):73-9.
11. Jain V, Ganpule A, Vyas J, Muthu V, Sabnis RB, Rajapurkar MM, et al. Management of non-neoplastic renal hemorrhage by transarterial embolization. Urology 2009;74:522–7.
12. Kim JW, Kim JY, Ahn ST, Park TY, Oh MM, Moon DG, Park HS. Spontaneous perirenal hemorrhage (Wunderlich syndrome): An analysis of 28 cases. Am J Emerg Med. 2019 Jan;37(1):45-47.

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