Advanced gastric cancer: the value of systemic and intraperitoneal chemotherapy

Advanced gastric cancer: the value of systemic and intraperitoneal chemotherapy

Authors

  • Federico Coccolini Emergency, General and Trauma Surgery dept., Bufalini hospital, Cesena, Italy
  • Paola Fugazzola Emergency, General and Trauma Surgery dept., Bufalini hospital, Cesena, Italy
  • Luca Ansaloni Emergency, General and Trauma Surgery dept., Bufalini hospital, Cesena, Italy
  • Massimo Sartelli General Surgery Department, Macerata Hospital, Macerata, Italy
  • Enrico Cicuttin Emergency, General and Trauma Surgery dept., Bufalini hospital, Cesena, Italy
  • Gioacchino Leandro National Institute of Gastroenterology “S. De Bellis” Research Hospital, Castellana Grotte, Italy
  • Gian Luigi de' Angelis Gastroenterology and Endoscopy Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Federica Gaiani Gastroenterology and Endoscopy Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Francesco Di Mario Gastroenterology and Endoscopy Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Matteo Tomasoni Emergency, General and Trauma Surgery dept., Bufalini hospital, Cesena, Italy
  • Fausto Catena General and Emergency Surgery dept., Maggiore hospital, Parma, Italy
DOI: https://doi.org/10.23750/abm.v89i8-S.7904

Keywords:

advanced gastric cancer, chemotherapy, hipec, intraperitoneal, surgery, carcinosis, metastasis

Abstract

Several possibilities in treating advanced gastric cancer exist. Radical surgery associated with chemotherapy represents the cornerstone. Which one is more effective among neoadjuvant, adjuvant or perioperative chemotherapy is still a matter of debate. Several innovative results showed the necessity to keep increasingly into consideration the intraperitoneal administration of chemotherapies. Moreover, classical drugs and their ways of administration should be combined with the new ones to improve results. Lastly the prevention of recurrence should be considered: one possibility is to administer intraperitoneal chemotherapy earlier in the therapeutic algorithm.

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Published

17-12-2018

Issue

Vol. 89 No. 8-S (2018): Topics in Gastroenterology - Focus on Upper GI diseases - vol. 1 - Editors: Francesco Di Mario, Chiara Miraglia, Gian Luigi de’ Angelis, Federica Gaiani

Section

REVIEWS

License

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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How to Cite

1.
Coccolini F, Fugazzola P, Ansaloni L, Sartelli M, Cicuttin E, Leandro G, et al. Advanced gastric cancer: the value of systemic and intraperitoneal chemotherapy. Acta Biomed [Internet]. 2018 Dec. 17 [cited 2024 Oct. 7];89(8-S):104-9. Available from: https://www.mattioli1885journals.com/index.php/actabiomedica/article/view/7904
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