Epidemiology and risk factors for diverticular disease

Epidemiology and risk factors for diverticular disease

Authors

  • Alessandra Violi Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Ginevra Cambiè Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Chiara Miraglia Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Alberto Barchi Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Antonio Nouvenne Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Mario Capasso Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Gioacchino Leandro National Institute of Gastroenterology “S. De Bellis” Research Hospital, Castellana Grotte, Italy
  • Tiziana Meschi Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Gian Luigi de' Angelis Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Francesco Di Mario Department of Medicine and Surgery, University of Parma, Parma, Italy

Keywords:

diverticulosis, diverticular disease, risk factors, epidemiology

Abstract

Diverticulosis of the colon is the most frequent anatomical alteration diagnosed at colonoscopy. The prevalence of the disease is higher in elderly patients over 65 years old, recent studies show an increment also in youngers over 40 years old. Even its large prevalence in the population, its pathophysiology still remain poorly understood. It’s widely accepted that diverticula are likely to be the result of complex interactions among genetic factors, alteration of colonic motility, lifestyle conditions such as smoking, obesity, alcohol consumption, fiber and meat intake with diet. Recently many authors considered also alterations in colonic microbiota composition, co-morbidity with diabetes and hypertension and the chronic assumption of certain medications like PPI, ARB and aspirin, as important risk factors for the development of diverticulosis. The aim of this narrative review is to summarise current knowledges on this topic.

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Published

17-12-2018

How to Cite

1.
Epidemiology and risk factors for diverticular disease. Acta Biomed [Internet]. 2018 Dec. 17 [cited 2024 Mar. 29];89(9-S):107-12. Available from: https://www.mattioli1885journals.com/index.php/actabiomedica/article/view/7924