Post-amputation neuroma of radial nerve in a patient with ephitelioid sarcoma: case report and literature review POST-AMPUTATION NEUROMA OF RADIAL NERVE

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Fabio Sandomenico
Antonio Corvino
Sergio Venanzio Setola
Igino Simonetti
Mauro Porcaro
Piero Trovato
Orlando Catalano
Antonella Petrillo


neuroma, peripheral nerves, tumors, sarcoma, ultrasound (US), magnetic resonance imaging (MRI)


Neuroma, also known as traumatic neuroma or amputation neuroma or stump neuroma, is a focal non neoplastic area of proliferative hyperplastic reaction secondary to peripheral nerve damage that commonly occurs after a focal trauma (acute or chronic) or surgery, such as amputation or partial transection. Neuromas are more commonly located in the lower limbs, followed by head and neck; other extremely rare sites include the ulnar nerve followed by the radial nerve and the brachial plexus. A radiologic plan is necessary to recognize soft tissue lesions with a neural origin and whether they are a true tumor or a pseudotumor such as a neuroma, fibrolipoma, or peripheral nerve sheath ganglion. In oncologic patients the appearance of post-surgical neuromas can produce problems in differential diagnosis with local recurrences. Therefore, with a combination of different imaging techniques, mainly ultrasound (US) and magnetic resonance imaging (MRI), it is possible to characterize neurogenic tumours safely, with a great impact on patient management and to plan an appropriate treatment. Here, we report the first case of post-amputation neuroma of radial nerve in a patient with clinical history of ephitelioid sarcoma with a short literature review.



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