@article{Franceschini_Bottau_Caimmi_Cardinale_Crisafulli_Liotti_Saretta_Bernardini_Mori_Caffarelli_2019, title={Mechanisms of hypersensitivity reactions induced by drugs}, volume={90}, url={https://www.mattioli1885journals.com/index.php/actabiomedica/article/view/8160}, DOI={10.23750/abm.v90i3-S.8160}, abstractNote={<p class="p1">Adverse drug reactions include drug hypersensitivity reactions (DHRs), which can be immunologically mediated or non-immunologically mediated. The high number of DHRs unconfirmed and/or self-reported is a frequent problem in daily clinical practice, with considerable impact on future prescription choices and patient health. It is important to distinguish between hypersensitivity and non-hypersensitivity reactions by adopting a structured diagnostic approach to confirm or discard the suspected drug, not only to avoid life-threatening reactions, but also to reduce the frequent over-diagnosis of DHRs.</p>}, number={3-S}, journal={Acta Biomedica Atenei Parmensis}, author={Franceschini, Fabrizio and Bottau, Paolo and Caimmi, Silvia and Cardinale, Fabio and Crisafulli, Giuseppe and Liotti, Lucia and Saretta, Francesca and Bernardini, Roberto and Mori, Francesca and Caffarelli, Carlo}, year={2019}, month={Jan.}, pages={44–51} }