Financial distress, psychological distress, and cost-related nonadherence among diabetic patients: Latent profile analysis

Financial distress, psychological distress, and cost-related nonadherence among diabetic patients: Latent profile analysis

Authors

  • Minh Hoang Le Can Tho University of Medicine and Pharmacy, Can Tho, Vietnam
  • Tran Nhat Phong Dao Can Tho University of Medicine and Pharmacy, Can Tho, Vietnam
  • Phi Phung Hoang Can Tho University of Medicine and Pharmacy, Can Tho, Vietnam
  • Thanh Binh Trieu Kien Giang Traditional Medicine Hospital, An Giang, Vietnam
  • Valeria Valeryevna Dorofeeva Peoples' Friendship University of Russia named after Patrice Lumumba, Moscow, Russia Federation
  • Van De Tran Can Tho University of Medicine and Pharmacy, Can Tho, Vietnam

Keywords:

cost-related nonadherence, diabetes, financial distress, psychological distress, Vietnam

Abstract

Background: Diabetes imposes a huge economic burden on individuals, their families, the national health system, and the economy as a whole. Research on financial distress has not yet been explored in the diabetic population in Vietnam. This study was conducted to determine the prevalence of financial distress and its associated demographic, psychological distress, and cost-related nonadherence factors in patients with diabetes.

Methods: A cross-sectional study was conducted on 311 patients with diabetes attending the outpatient department of a public hospital in An Giang, Vietnam, from April 2025 to May 2025. Newly diagnosed, controlled, and ongoing-therapy patients were included and classified by current management into lifestyle modification, oral medications, or insulin therapy (alone or in combination). Latent Profile Analysis (LPA) was performed to classify patients with diabetes into their most likely group based on their financial distress profile.

Results: LPA identified three latent profiles: none (13.5%), mild (56.3%), and moderate (30.2%) financial distress. The ROC analysis identified a score of 25.5 as the optimal threshold for distinguishing between none and mild/moderate financial distress, with a sensitivity of 100% and a specificity of 98.9%. Multinomial logistic regression analysis revealed that higher psychological distress, being a worker or public employee, and cost-related nonadherence were significantly associated with having mild or moderate financial distress.

Conclusion: Psychological distress and cost-related nonadherence are factors influencing financial distress in patients with diabetes. Future interventions should target these factors to help reduce the level of financial distress in this population.

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Published

2026-01-30

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Original research

How to Cite

1.
Le MH, Dao TNP, Hoang PP, Trieu TB, Dorofeeva VV, Tran VD. Financial distress, psychological distress, and cost-related nonadherence among diabetic patients: Latent profile analysis. Ann Ig. 2026;38(1):17716. doi:10.7416/ai.2026.17716