Progressive Disseminated Histoplasmosis in an Immunocompetent Host: A Rare Presentation of an Uncommon Disease

Progressive Disseminated Histoplasmosis in an Immunocompetent Host: A Rare Presentation of an Uncommon Disease

Authors

  • Mehul Agarwal Department of Pulmonary Medicine, All India Institute of Medical Sciences (AIIMS), Jodhpur
  • Manohar Lal Gupta Department of Pulmonary Medicine,Santokba Durlabhji Memorial Hospital, Jaipur
  • Benhur Joel Shadrach Pulmonary, Critical care & Sleep Medicine, Department of Pulmonary Medicine, All India Institute of Medical Sciences (AIIMS), Jodhpur
  • Neha Bharti Department of Anesthesiology and critical care, All India Institute of Medical Sciences (AIIMS), Jodhpur

Keywords:

Disseminated Histoplasmosis, endemic, immunocompetent, biopsy

Abstract

Disseminated Histoplasmosis, a systemic fungal infection caused by Histoplasma capsulatum is predominantly seen in immunocompromised cases. It is usually endemic, although sporadic cases have been reported. Following initial infection to the lungs, it disseminates to various organs by lymphatic and hematogenous routes. Clinical features are non-specific and depend on the extent and severity of organ involvement. A Biopsy is required for diagnosis and timely intervention decreases morbidity and mortality. Our case report describes an atypical association of progressive disseminated Histoplasmosis with bone marrow involvement in an immunocompetent adult from a non-endemic region and alerts the clinicians to a rare yet life-threatening mycosis.

References

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Published

06-10-2021

Issue

Section

Case Reports: General Surgery and Miscellanea

How to Cite

1.
Agarwal M, Gupta ML, Shadrach BJ, Bharti N. Progressive Disseminated Histoplasmosis in an Immunocompetent Host: A Rare Presentation of an Uncommon Disease . Acta Biomed [Internet]. 2021 Oct. 6 [cited 2024 Jul. 20];92(S1):e2021134. Available from: https://www.mattioli1885journals.com/index.php/actabiomedica/article/view/10213