Hormone resistance in children: what primary care physicians need to know

Hormone resistance in children: what primary care physicians need to know


  • Kotb Metwalley Department of Pediatrics, Faculty of Medicine, Assiut University, Assiut, Egypt.
  • Hekma Saad Farghaly Department of Pediatrics, Faculty of Medicine, Assiut University, Assiut, Egypt.


hormone resistance, Laron syndrome, pseudohypoparathyroidism, insulin resistance, thyroid hormone resistance


Hormone resistance is defined as a reduced or absence of  target tissues responsiveness to a hormone, where the presentation is related to either a relative lack or excess of hormones. Various disorders of hormone resistance were encountered including, Laron syndrome, nephrogenic diabetes insipidus, thyroid hormone resistance syndrome, pseudohypoparathyroidism, insulin resistance, familial glucocorticoid deficiency, pseudohypoaldosteronism, X linked hypophosphatemic rickets  and androgen insensitivity syndrome. The article gives a summary that presents, in concentrated form, what the primary care physicians need to know about recognition,  clinical presentation, diagnosis, and management  of various hormone resistance in children.


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How to Cite

Metwalley K, Farghaly H. Hormone resistance in children: what primary care physicians need to know. Acta Biomed [Internet]. 2021 Sep. 2 [cited 2024 Jul. 24];92(4):e2021255. Available from: https://www.mattioli1885journals.com/index.php/actabiomedica/article/view/11613