Hematological Parameters as Diagnostic Factors: Correlation with Severity of COVID-19

Hematological Parameters as Diagnostic Factors: Correlation with Severity of COVID-19

Authors

  • Masoomeh Dadkhah Ardabil University of Medical Sciences
  • Somaieh Matin
  • Elham Safarzadeh
  • Nima Rezaei
  • Mohammad Negaresh
  • Hossein Salehzadeh
  • Samira Matin
  • Amirhossein Sharifiazar
  • Malek Abazari

Keywords:

COVID-19; Hematological parameters; Prognosis; Severity

Abstract

Bachground and aim: Coronavirus disease 2019(COVID-19), which is the pandemic of 21st century, is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Prognostic factors play an essential role in predicting the patients who need more care. Therefore, the current study aimed to investigate the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) ratio as discriminated indexes in prognosis of patients with COVID‐19. Methods: Age, NLR, PLR, white blood cell (WBC), neutrophil count, lymphocyte count and platelet from 1007 hospitalized patients with COVID-19, who were admitted to two referring hospitals  in Ardabil, North Western Iran. All confirmed cases divided into non-severe and severe groups. Results:  534 (53.4%) males and 473 (47.3 %) females with mean age of 52 years were enrolled in this study. Patients with severe COVID-19 have lower counts of lymphocyte, but have higher NLR, comparing to non-severe patients (P = 0.001). Conclusion: Elevated NLR can be assumed as an independent biomarker, which could provide a crucial indicator in the monitoring patients with COVID-19 on admission. Increased NLR was correlated with the severity of COVID-19. Assessment of NLR could be proposed to identify high risk individuals with COVID-19.

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Published

11-05-2022

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Section

ORIGINAL INVESTIGATIONS/COMMENTARIES - SPECIAL COVID19

How to Cite

1.
Dadkhah M, Matin S, Safarzadeh E, Rezaei N, Negaresh M, Salehzadeh H, et al. Hematological Parameters as Diagnostic Factors: Correlation with Severity of COVID-19 . Acta Biomed [Internet]. 2022 May 11 [cited 2024 Jul. 21];93(2):e2022061. Available from: https://www.mattioli1885journals.com/index.php/actabiomedica/article/view/12320