Rapidly progressive ischemic strokes and transient antiphospholipid syndrome during a mild SARS-CoV-2 infection

Rapidly progressive ischemic strokes and transient antiphospholipid syndrome during a mild SARS-CoV-2 infection

Authors

  • Roberto Sartor a:1:{s:5:"en_US";s:52:"Clinical Neurology, Udine University Hospital, Udine";}
  • Francesca Capozzoli Department of Neurology, ASFO Santa Maria degli Angeli Hospital of Pordenone, Pordenone, Italy
  • Sergio Venturini Department of Infectious Diseases, ASFO Santa Maria degli Angeli Hospital of Pordenone, Pordenone, Italy
  • Massimo Crapis Department of Infectious Diseases, ASFO Santa Maria degli Angeli Hospital of Pordenone, Pordenone, Italy
  • Paolo Passadore Department of Neurology, ASFO Santa Maria degli Angeli Hospital of Pordenone, Pordenone, Italy
  • Mariarosaria Valente Clinical Neurology, Udine University Hospital, Udine, Italy

Keywords:

Covid-19, SARS-CoV-2, stroke, multiple, antiphospholipid, ischemic, mild

Abstract

SARS-CoV-2 infection is associated with an increased risk of thrombotic events, especially during severe forms of disease. Here we describe the clinical history of a patient with a mild form of Covid-19 infection presenting with multiple cerebral ischemic lesions that evolved in an atypical way.

References

GALSTYAN GM. Coagulopathy in COVID-19. Pulmonologiya 2020;30(5):645-657. doi:10.18093/0869-0189-2020-30-5-645-657

ASAKURA H, OGAWA H. COVID-19-associated coagulopathy and disseminated intravascular coagulation. Int J Hematol 2021;113(1):45-57. doi:10.1007/s12185-020-03029-y

AGHAYARI SHEIKH NESHIN S, SHAHJOUEI S, KOZA E, ET AL. Stroke in SARS-CoV-2 Infection: A Pictorial Overview of the Pathoetiology. Front Cardiovasc Med 2021;8. doi:10.3389/fcvm.2021.649922

KICHLOO A, DETTLOFF K, ALJADAH M, ET AL. COVID-19 and Hypercoagulability: A Review. Clin Appl Thromb 2020;26. doi:10.1177/1076029620962853

VOGRIG A, GIGLI GL, BNÀ C, MORASSI M. Stroke in patients with COVID-19: Clinical and neuroimaging characteristics. Neurosci Lett 2021;743. doi:10.1016/j.neulet.2020.135564

KORALNIK IJ, TYLER KL. COVID-19: A Global Threat to the Nervous System. Ann Neurol 2020;88(1):1-11. doi:10.1002/ana.25807

HESS DC, ELDAHSHAN W, RUTKOWSKI E. COVID-19-Related Stroke. Transl Stroke Res 2020;11(3):322-325. doi:10.1007/s12975-020-00818-9

IMOTO W, KAGA S, NODA T, OSHIMA K, MIZOBATA Y, KAKEYA H. Coronavirus disease with multiple infarctions. Qjm 2020;113(12):907-908. doi:10.1093/qjmed/hcaa240

DÍAZ-PÉREZ C, RAMOS C, LÓPEZ-CRUZ A, ET AL. Acutely altered mental status as the main clinical presentation of multiple strokes in critically ill patients with COVID-19. Neurol Sci 2020;41(10):2681-2684. doi:10.1007/s10072-020-04679-w

ZAYET S, KLOPFENSTEIN T, KOVẚCS R, STANCESCU S HB. Acute Cerebral Stroke with Multiple Infarctions and COVID-19, France, 2020. Emerg Infect Dis 2020;26(9):2258-2260. https://pubmed.ncbi.nlm.nih.gov/32453685/

GUILLAN M, VILLACIEROS-ALVAREZ J, BELLIDO S, PEREZ-JORGE PEREMARCH C, SUAREZ-VEGA VM, ARAGONES-GARCIA M, ET AL. Unusual simultaneous cerebral infarcts in multiple arterial territories in a COVID-19 patient. Thromb Res 2020;193:107-109.

ZHANG Y, XIAO M, ZHANG S, XIA P, CAO W, JIANG W, ET AL. Coagulopathy and antiphospholipid antibodies in patients with covid-19. N Engl J Med 2020;382(17):E38-E38.

CERASTI D, ORMITTI F, PARDATSCHER S, MALCHIODI L, PICETTI E, MENOZZI R RS. Multiple Acute Ischemic Strokes in a COVID-19 Patient: a Case Report. SN Compr Clin Med 2020;2(8):1213-1217.

Downloads

Published

07-06-2022

How to Cite

1.
Sartor R, Capozzoli F, Venturini S, Crapis M, Passadore P, Valente M. Rapidly progressive ischemic strokes and transient antiphospholipid syndrome during a mild SARS-CoV-2 infection. Acta Biomed [Internet]. 2022 Jun. 7 [cited 2024 Jul. 27];93(S1):e2022107. Available from: https://www.mattioli1885journals.com/index.php/actabiomedica/article/view/12609