IgA Vasculitis following AstraZeneca/Oxford COVID-19, case report

IgA Vasculitis following AstraZeneca/Oxford COVID-19, case report


  • Nasser Alzoabi
  • Jamal Alqahtani
  • Bader Algamdi
  • Nada Alghamdi a:1:{s:5:"en_US";s:39:"Imam Abdulrahman Bin Faisal University ";}
  • Ayesha Ahmad
  • Gaeda Alkaltham
  • Tala Beidas
  • Omar Alakloby


IgA vasculitis, AstraZeneca/Oxford COVID-19 vaccine, skin biopsy.


Immunoglobulin A (IgA) vasculitis, also known as Henoch–Schönlein purpura, is an immune-mediated vasculitis that affects small vessels. IgA vasculitis could be triggered by numerous conditions including infectious and non-infectious conditions. So far, few reported cases of Covid-19 vaccines related vasculitis. We report a case of IgA vasculitis after AstraZeneca/Oxford COVID-19 vaccine. A 29-year-old healthy man who developed purpuric skin lesions one week after his second AstraZeneca/Oxford COVID-19 vaccine which complicated by glomerulonephritis and gastrointestinal involvement. Skin biopsy revealed fibrinoid necrosis and leukocytoclasia consistent with small vessel vasculitis. Due to the temporal association, AstraZeneca/Oxford COVID-19 vaccine-related IgA vasculitis would be the most likely explanation.


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How to Cite

IgA Vasculitis following AstraZeneca/Oxford COVID-19, case report. Acta Biomed [Internet]. 2023 Dec. 5 [cited 2024 Apr. 25];94(6):e2023074. Available from: https://www.mattioli1885journals.com/index.php/actabiomedica/article/view/12959