Correlation between serum vitamin D levels with severity of community acquired Pneumonia in hospitalized patients over sixty years old in Indonesia

Correlation between serum vitamin D levels with severity of community acquired Pneumonia in hospitalized patients over sixty years old in Indonesia

Authors

  • Marwan Febrian Department of Internal Medicine, Faculty of Medicine, Hasanuddin University
  • Agus Sudarso Department of Internal Medicine, Faculty of Medicine, Hasanuddin University
  • Muhammad Ilyas Department of Internal Medicine, Faculty of Medicine, Hasanuddin University
  • Syakib Bakri Department of Internal Medicine, Faculty of Medicine, Hasanuddin University
  • Andi Makbul Aman Department of Internal Medicine, Faculty of Medicine, Hasanuddin University
  • Arifin Seweng Department of Internal Medicine, Faculty of Medicine, Hasanuddin University

Keywords:

Vitamin D, Community Acquired Pneumonia, Elderly

Abstract

Background and aim: Old-aged persons commonly experience vitamin D deficiency due to many factors such as insufficient vitamin D intake, multiple medications, low sun exposure, and chronic kidney disease, thus increases susceptibility to infections. Community Acquired Pneumonia (CAP) is common in old-aged persons with a high morbidity rate. Its mortality rates can even reach 50-70% if accompanied by comorbidities. This study aimed to describe the correlation between CAP severity with serum vitamin D levels in hospitalized old-aged patients. Methods: This is an observational study with cross-sectional design, involving 82 hospitalized old-aged patients with diagnosis of CAP. Blood samples was collected in order to measure serum Vitamin D levels. Data normality was tested with Kolmogorov-Smirnov test, while Chi Square and Mann-Whitney test was utilized for statistical analysis. Statistical significance was described as p value < 0.05. Results: Average serum vitamin D levels were significantly lower in severe patients than in non-severe groups (p<0.05). The percentage of patients with vitamin D deficiency was also higher in the severe group compared to the non-severe group (p<0.05). Conclusions: There is a significant correlation between serum vitamin D levels and the severity of CAP in hospitalized old-aged patients. 

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Published

21-06-2024

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Section

ORIGINAL CLINICAL RESEARCH

How to Cite

1.
Febrian M, Sudarso A, Ilyas M, Bakri S, Makbul Aman A, Seweng A. Correlation between serum vitamin D levels with severity of community acquired Pneumonia in hospitalized patients over sixty years old in Indonesia. Acta Biomed [Internet]. 2024 Jun. 21 [cited 2024 Jul. 20];95(3):e2024051. Available from: https://www.mattioli1885journals.com/index.php/actabiomedica/article/view/15504