Acute pancreatitis as a rare adverse event following COVID-19 vector-based vaccination: A case report

Bayan Nurgaliyeva; Aizhan Moldakaryzova; Saken Khaidarov; Zhannat Aldasheva

doi:10.23750/abm.v96i6.17277

Acute pancreatitis as a rare adverse event following COVID-19 vector-based vaccination: A case report

Authors

Bayan Nurgaliyeva Department of propaedeutic of internal diseases, Kazakh National Medical University named after S. Asfendyarov, Almaty, Kazakhstan; KazMed Company LLP Outpatient Clinic, Almaty https://orcid.org/0000-0003-2555-8644
Aizhan Moldakaryzova Department of Molecular Biology and Medical Genetics, Kazakh National Medical University named after S. Asfendyarov, Almaty, Kazakhstan https://orcid.org/0000-0003-0186-978X
Saken Khaidarov Department of Molecular Biology and Medical Genetics, Kazakh National Medical University named after S. Asfendyarov, Almaty, Kazakhstan https://orcid.org/0000-0001-7770-8427
Zhannat Aldasheva Kazakhstan Medical University “Kazakhstan School of Public Health”, Almaty, Kazakhstan https://orcid.org/0009-0004-8556-8670

Keywords:

acute pancreatitis, COVID 19, vector vaccine, adverse event, case report

Abstract

Background: Acute pancreatitis (AP) has been reported rarely after vaccination against SARS‑CoV‑2.

Case: We describe a 41‑year‑old vegetarian, non‑smoking male who developed AP five days after the first dose of the adenoviral vector vaccine Gam‑COVID‑Vac (Sputnik V). On admission serum amylase was 3600 U/L and abdominal ultrasound demonstrated an enlarged, oedematous pancreas without gall‑stones. The patient responded to conservative therapy and was discharged after seven days.

Conclusion: Although causal inference cannot be drawn from a single observation, clinicians should remain aware of AP as a potential event after vector‑based COVID‑19 vaccination.

Author Biography

Bayan Nurgaliyeva, Department of propaedeutic of internal diseases, Kazakh National Medical University named after S. Asfendyarov, Almaty, Kazakhstan; KazMed Company LLP Outpatient Clinic, Almaty

The cheif of the department the propeudeutics of the internal diseases of Kazakh National Medical University

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