Case report of atypical endometrial stromal cells in an endometrial polyp and osteoclastic like giant cells in leiomyoma in the same patient: Is it a coincidence or is it a result of Tamoxifen treatment?

Case report of atypical endometrial stromal cells in an endometrial polyp and osteoclastic like giant cells in leiomyoma in the same patient: Is it a coincidence or is it a result of Tamoxifen treatment?

Authors

  • Çiğdem Öztürk University of Health Sciences, Bağcılar Training and Research Hospital, Pathology Department, İstanbul
  • Tuğçe Çay University of Health Sciences, Bağcılar Training and Research Hospital, Pathology Department, İstanbul
  • Seza Tetikkurt University of Health Sciences, Bağcılar Training and Research Hospital, Pathology Department, İstanbul
  • Emre Volkan Kasımogullar University of Health Sciences, Bağcılar Training and Research Hospital, Gynecology and Obstetrics Clinic, İstanbul
  • Tolga Karacan University of Health Sciences, Bağcılar Training and Research Hospital, Gynecology and Obstetrics Clinic, İstanbul

Keywords:

atypical endometrial stromal  cells,, osteoclastic like giant cells, leiomyoma, tamoxifen treatment

Abstract

Atypical stromal cells are rarely identified in the endometrial polyps of the female lower genital system. These cells are suggested to develop due to a degenerative or reactive phenomenon. And osteoclastic like giant cells, which have been reported in many epithelial and mesenchymal tumors of uterus, may develop because of a degenerative or a reactive process. In this case report, we present a breast cancer patient who was commenced on Tamoxifen treatment presenting with formation of both atypical stromal cells in an endometrial polyp and osteoclastic like giant cells in the leiomyoma of the uterus. Patients who are treated with Tamoxifen should be followed meticulously to detect tumoral or proliferative lesions of endometrium and myometrium because of the adverse effects of tamoxifen on uterus. (www.actabiomedica.it)

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Published

21-03-2019

Issue

Section

CASE REPORTS

How to Cite

1.
Öztürk Çiğdem, Çay T, Tetikkurt S, Kasımogullar EV, Karacan T. Case report of atypical endometrial stromal cells in an endometrial polyp and osteoclastic like giant cells in leiomyoma in the same patient: Is it a coincidence or is it a result of Tamoxifen treatment?. Acta Biomed [Internet]. 2019 Mar. 21 [cited 2024 Jul. 20];90(4):572-6. Available from: https://www.mattioli1885journals.com/index.php/actabiomedica/article/view/7746