Risk of tumor implantation in percutaneous endoscopic gastrostomy in the upper aerodigestive tumors

Risk of tumor implantation in percutaneous endoscopic gastrostomy in the upper aerodigestive tumors

Authors

  • Francesca Vincenzi Gastroenterology and Endoscopy Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Giuseppina De Caro Gastroenterology and Endoscopy Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Federica Gaiani Gastroenterology and Endoscopy Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Fabiola Fornaroli Gastroenterology and Endoscopy Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Roberta Minelli Gastroenterology and Endoscopy Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Gioacchino Leandro National Institute of Gastroenterology “S. De Bellis” Research Hospital, Castellana Grotte, Italy
  • Francesco Di Mario Gastroenterology and Endoscopy Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Gian Luigi de' Angelis Gastroenterology and Endoscopy Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy

Keywords:

percutaneous endoscopic gastrostomy, metastasis, aerodigestive tumors

Abstract

Percutaneous endoscopic gastrostomy (PEG) has become a mainstay in providing enteral access for patients with obstructive head, neck and esophageal tumors. Tumor cell implantation is a rare complication in patients with aerodigestive cancers, who have undergone PEG tube placement. The objective of this review is to determine the incidence and contributing risk factors leading to the implantation of metastases into the abdominal wall following PEG placement. A comprehensive review of the literature in PUBMED (2008-2018) was performed.  The literature search revealed reports of more than 50 cases of abdominal wall metastases after PEG placement. As most of these studies were case reports, the exact rate of metastasis remains unknown. Generally pharyngoesophageal location of primary cancer (100%), squamous cell histology (98%), poorly differentiated tumor cells (92%), advanced pathological stage (97%), and large primary cancer size were identified as strong risk factors for the development of stomal metastasis. Abdominal wall metastases following PEG placement are a rare but serious complication in patients with head and neck malignancy.

Downloads

Published

17-12-2018

How to Cite

1.
Risk of tumor implantation in percutaneous endoscopic gastrostomy in the upper aerodigestive tumors. Acta Biomed [Internet]. 2018 Dec. 17 [cited 2024 Jun. 13];89(8-S):117-21. Available from: https://www.mattioli1885journals.com/index.php/actabiomedica/article/view/7894

Most read articles by the same author(s)

1 2 3 4 5 6 > >>