Advanced gastric cancer: the value of surgery

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Paola Fugazzola
Luca Ansaloni
Massimo Sartelli
Fausto Catena
Enrico Cicuttin
Gioacchino Leandro
Gian Luigi de' Angelis
Federica Gaiani
Francesco Di Mario
Matteo Tomasoni
Federico Coccolini

Keywords

advanced gastric cancer, chemotherapy, hipec, intraperitoneal, surgery, definition, metastasis, carcinosis

Abstract

Gastric cancer is a common disease with high mortality. The definition of advanced gastric cancer is still debated. Radical surgery associated to appropriate systemic and intra-abdominal chemotherapy is the gold standard treatment. In presence of peritoneal carcinosis, reaching a complete cytoreduction is the key to achieve long-term survival. Adequate lymphadenectomy is also fundamental. Conversion therapy could be applied to selected IV stage patients. No definitive evidences exist regarding the oncological and surgical superiority of mini-invasive approaches over the classical open techniques.

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