Epidemiology and risk factors of pancreatic cancer

Epidemiology and risk factors of pancreatic cancer

Authors

  • Mario Capasso Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Marilisa Franceschi Endoscopy Unit, Departement of Surgery, ULSS7-Pedemontana, Santorso Hospital, Santorso (VI), Italy
  • Kryssia Isabel Rodriguez-Castro Endoscopy Unit, Departement of Surgery, ULSS7-Pedemontana, Santorso Hospital, Santorso (VI), Italy
  • Pellegrino Crafa Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Ginevra Cambiè Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Chiara Miraglia Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Alberto Barchi Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Antonio Nouvenne Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Gioacchino Leandro National Institute of Gastroenterology “S. De Bellis” Research Hospital, Castellana Grotte, Italy
  • Tiziana Meschi Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Gian Luigi de' Angelis Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Francesco Di Mario Department of Medicine and Surgery, University of Parma, Parma, Italy

Keywords:

pancreatic cancer, pancreatic adenocarcinoma, epidemiology, risk factors

Abstract

The most frequent pancreatic cancer is pancreatic adenocarcinoma. It has high and early locally and distant invasiveness; this is the reason why it often shows little sign or symptoms in early stage and poor prognosis after the diagnosis, frequently in advanced stage. Although it is possible to detect this tumor in early stage because of its neoplastic precursor (PanINs). Epidemiological data shows that pancreatic cancer is not very common but obvious it is one of the most neoplastic death-cause in the world. The trend of incidence is quite increasing through years, proportionally to the increase of risk factors. About risk factors, it is not easy to detect in all the cases but it is known the role of some of that: there are hereditary risk factors, such as genetic pattern like HBOC, HNPCC, FAP, PJS, FAMMM, HP and CF and environmental ones (modifiable) such as smoke, alcohol consumption, chronic pancreatitis, obesity and diabetes mellitus. This narrative review aims to analyze the epidemiological data of pancreatic cancer and associated risk factors.

Downloads

Published

17-12-2018

How to Cite

1.
Epidemiology and risk factors of pancreatic cancer. Acta Biomed [Internet]. 2018 Dec. 17 [cited 2024 Apr. 25];89(9-S):141-6. Available from: https://www.mattioli1885journals.com/index.php/actabiomedica/article/view/7923

Most read articles by the same author(s)

1 2 3 4 5 6 > >>