Striae distensae in adolescents: A mini review

Main Article Content

Heba Elsedfy


Adolescents, striae distensae, stretch marks


Striae distensae or stretch marks are mainly a cosmetic concern. They commonly occur in adolescence and in pregnant women. Although, generally more common in females; physiological striae atrophicae of adolescence are more common in males. The pathophysiology is multifactorial with mechanical stretching of the skin being the most important. Despite of an abundance of treatment modalities none is 100% effective. 



Download data is not yet available.


Metrics Loading ...
Abstract 201 | PDF Downloads 96


1. Rogalski C, Haustein UF, Glander HJ, Paasch U. Extensive striae distensae as a result of topical corticosteroid therapy in psoriasis vulgaris. Acta Derm Venereol. 2003;83:54-55.
2. Stamatas GN, Lopes-DaCunha A, Nkengne A, Bertin C. Biophysical properties of Striae Distensae evaluated in vivo using non-invasive assays. Skin Res Technol. 2015;21:254-258.
3. Tong PL, Qin J, Cooper CL, Lowe PM, Murrell DF, Kossard S, Ng LG, Roediger B, Weninger W, Haass NK. A quantitative approach to histopathological dissection of elastin-related disorders using multiphoton microscopy. Br J Dermatol. 2013;169:869-879.
4. Mitts TF, Jimenez F, Hinek A. Skin biopsy analysis reveals predisposition to stretch mark formation. Aesthet Surg J. 2005;25:593-600.
5. Wang F, Calderone K, Do TT, Smith NR, Helfrich YR, Johnson TRB, Kang S, Voorhees JJ, Fisher GJ. Severe disruption and disorganization of dermal collagen fibrils in early striae gravidarum. Br J Dermatol. 2018;178:749-760.
6. Wang F, Calderone K, Smith NR, Do TT, Helfrich YR, Johnson TR, Kang S, Voorhees JJ, Fisher GJ. Marked disruption and aberrant regulation of elastic fibres in early striae gravidarum. Br J Dermatol. 2015;173:1420-1430.
7. Keen MA. Striae distensae: What’s new at the horizon? BJMP 2016;9:a919
8. Cho S, Park ES, Lee DH, Li K, Chung JH. Clinical features and risk factors for striae distensae in Korean adolescents. J Eur Acad Dermatol Venereol. 2006;20:1108-1113.
9. Al-Himdani S, Ud-Din S, Gilmore S, Bayat A. Striae distensae: a comprehensive review and evidence-based evaluation of prophylaxis and treatment. Br J Dermatol. 2014;170:527-547.
10. Cordeiro RC, Zecchin KG, de Moraes AM. Expression of estrogen, androgen, and glucocorticoid receptors in recent striae distensae. Int J Dermatol. 2010;49:30-32.
11. McKusick VA. Transverse striae distensae in the lumbar area in father and two sons. Birth Defects Orig Artic Ser. 1971;7:260-261.
12. Cordeiro RC, de Moraes AM. Striae Distensae: Physiopathology. Surg Cosmet Dermatol. 2009;1:137-140.
13. Tung JY, Kiefer AK, Mullins M, Francke U, Eriksson N. Genome-wide association analysis implicates elastic microfibrils in the development of nonsyndromic striae distensae. J Invest Dermatol. 2013;133:2628-2631.
14. Leung AK, Barankin B. Physiological striae atrophicae of adolescence with involvement of the upper back. Case Rep Pediatr. 2013;2013:386094. doi:10.1155/2013/386094
15. Elshimy N, Gandhi A. A teenager with lumbar striae distensae (when a bruise is not a bruise). BMJ Case Rep. 2013;2013:bcr2013201962. Published 2013 Dec 18. doi:10.1136/bcr-2013-201962.
16. Lokhande AJ, Mysore V. Striae distensae treatment review and update. Indian Dermatol Online J. 2019;10:380–395.
17. Boozalis E, Grossberg AL, Puttgen KB, Heath CR, Cohen BA. Demographic characteristics of teenage boys with horizontal striae distensae of the lower back. Pediatr Dermatol. 2018;35:59-63.
18. Youssef SES, El-Khateeb EA, Aly DG, Moussa MH. Striae distensae: Immunohistochemical assessment of hormone receptors in multigravida and nulligravida. J Cosmet Dermatol. 2017;16:279-286.
19. Valente DS, Zanella RK, Doncatto LF, Padoin AV. Incidence and risk factors of Striae Distensae following breast augmentation surgery: a cohort study. PLoS One. 2014;9(5):e97493. doi: 10.1371/journal.pone.0097493. eCollection 2014.
20. Adam JE, Craig G. Striae and their relation to topical steroid therapy. Can Med Assoc J. 1965;92:289–291.
21. Atwal GS, Manku LK, Griffiths CE, Polson DW. Striae gravidarum in primiparae. Br J Dermatol. 2006;155:965–969.
22. Ud-Din S, McGeorge D, Bayat A. Topical management of striae distensae (stretch marks): prevention and therapy of striae rubrae and albae. J Eur Acad Dermatol Venereol. 2016;30:211–222.
23. Hague A, Bayat A. Therapeutic targets in the management of striae distensae: A systematic review. J Am Acad Dermatol. 2017;77:559–568.
24. Lokhande AJ, Mysore V. Striae Distensae Treatment Review and Update. Indian Dermatol Online J. 2019;10:380–395.
25. Liu L, Ma H, Li Y. Interventions for the treatment of stretch marks: a systematic review. Cutis. 2014;94:66–72.
26. Farahnik B, Park K, Kroumpouzos G, Murase J. Striae gravidarum: Risk factors, prevention, and management. Int J Womens Dermatol. 2016;3:77–85.
27. O'Connor AA, Lowe PM, Shumack S, Lim AC. Chemical peels: A review of current practice. Australas J Dermatol. 2018;59:171–181.
28. Karia UK, Padhiar BB, Shah BJ. Evaluation of Various Therapeutic measures in striae rubra. J Cutan Aesthet Surg. 2016;9:101–105.
29. Kim IS, Park KY, Kim BJ, Kim MN, Kim CW, Kim SE. Efficacy of intradermal radiofrequency combined with autologous platelet-rich plasma in striae distensae: a pilot study. Int J Dermatol. 2012;51:1253–1258.
30. Gold MH. Update on fractional laser technology. J Clin Aesthet Dermatol. 2010;3:42–50.
31. Hou A, Cohen B, Haimovic A, Elbuluk N. Microneedling: A Comprehensive Review. Dermatol Surg. 2017;43:321–339.
32. Bitencourt S, Lunardelli A, Amaral RH, Dias HB, Boschi ES, de Oliveira JR. Safety and patient subjective efficacy of using galvanopuncture for the treatment of striae distensae. J Cosmet Dermatol. 2016;15:393–398.
33. Faurschou A, Olesen AB, Leonardi-Bee J, Haedersdal M. Lasers or light sources for treating port-wine stains. Cochrane Database Syst Rev. 2011 Nov 9;(11):CD007152. doi: 10.1002/14651858.CD007152.pub2.
34. Wollina U, Goldman A. Management of stretch marks (with a focus on striae rubrae). J Cutan Aesthet Surg. 2017;10:124–129.
35. Sadick NS, Magro C, Hoenig A. Prospective clinical and histological study to evaluate the efficacy and safety of a targeted high-intensity narrow band UVB/UVA1 therapy for striae alba. J Cosmet Laser Ther. 2007;9:79–83.
36. Elsaie ML, Baumann LS, Elsaaiee LT. Striae distensae (stretch marks) and different modalities of therapy: an update. Dermatol Surg. 2009;35:563–573.