Apathetic encephalopathy in thyreotoxicosis: an unsual cause of wernicke encephalopathy and osmotic demyelinating syndrome: An unsual cause of wernicke encephalopathy and osmotic demyelinating syndrome

Apathetic encephalopathy in thyreotoxicosis: an unsual cause of wernicke encephalopathy and osmotic demyelinating syndrome

An unsual cause of wernicke encephalopathy and osmotic demyelinating syndrome

Authors

  • Carlotta Mutti Neurology Department, Parma Hospital
  • Rosario Ciliento Neurology Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Liborio Parrino Sleep Medicine Center, Neurology Unit, Department of General and Specialistic Medicine, University Hospital of Parma, Parma, Italy
  • Irene Florindo Neurology Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Giovanni Pavesi Neurology Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Lucia Zinno Neurology Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy

Keywords:

Apathetic Encephalopathy, Thyrotoxicosis Wernicke encephalopathy, osmotic demyelination syndrome

Abstract

Non-alcoholic Wernicke Encephalopathy (WE) is an overlooked complication of malnourishment in all its forms including undernutrition, inadequate vitamine intake and endocrinological diseases. Both delay in treatment and overtreatment can lead to severe neurological life-long consequences. Inadequate management in patients with chronic malnutrition may cause abrupt osmolytes unbalance and subsequent osmotic demyelination syndromes.  We describe a 65-year old man with apathetic encephalopathy caused by thyreotoxicosis and associated with malnutrition and severe thiamine depletion.

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Published

05-02-2021

How to Cite

1.
Mutti C, Ciliento R, Parrino L, Florindo I, Pavesi G, Zinno L. Apathetic encephalopathy in thyreotoxicosis: an unsual cause of wernicke encephalopathy and osmotic demyelinating syndrome: An unsual cause of wernicke encephalopathy and osmotic demyelinating syndrome. Acta Biomed [Internet]. 2021 Feb. 5 [cited 2024 Jul. 24];92(1):e2021055. Available from: https://www.mattioli1885journals.com/index.php/actabiomedica/article/view/9473