Clinical utility of Dual Energy Computed Tomography in gout: current concepts and applications

Clinical utility of Dual Energy Computed Tomography in gout: current concepts and applications


  • Marina Carotti Department of Radiology – Division of Special and Pediatric Radiology, University Hospital “Umberto I – Lancisi –Salesi”- Universiy Politecnica Marche - Via Conca 71, 60126 Ancona, AN, Italy.
  • Fausto Salaffi Rheumatological Clinic, Department of Molecular and Clinical Sciences, University Politecnica Marche – Ancona, Italy
  • Emilio Filippucci Rheumatological Clinic, Department of Molecular and Clinical Sciences, University Politecnica Marche – Ancona, Italy
  • Giacomo Aringhieri Radiologia Diagnostica ed Interventistica, Dipartimento di ricercar Traslazionale e Nuove Tecnologie in Medicina e Chirurgia, Università di Pisa, Pisa, Italy
  • Federico Bruno Department of Biotechnology and Applied Clinical Science, University of L'Aquila, L’Aquila, Italy
  • Sabrina Giovine Department of Radiology, SG Moscati Hospital, ASL Caserta, Aversa, Caserta, Italy
  • Francesco Gentili Department of Medicine and Surgery (DiMec), Section of Radiology, University of Parma, Maggiore Hospital, Parma, Italy
  • Chiara Floridi University Politecnica delle Marche, Department of Clinical Special and Dental Sciences, Ancona, Italy
  • Alessandra Borgheresi Department of Radiology – Division of Special and Pediatric Radiology, University Hospital “Umberto I – Lancisi –Salesi”- University Politecnica Marche – Ancona, Italy
  • Massimo De Filippo Department of Medicine and Surgery (DiMec), Section of Radiology, University of Parma, Maggiore Hospital, Parma, Italy
  • Carlo Masciocchi Department of Biotechnology and Applied Clinical Science, University of L'Aquila, L’Aquila, Italy
  • Antonio Barile Department of Applied Clinical Science and Biotechnology, University of L'Aquila, L’Aquila, Italy
  • Andrea Giovagnoni Department of Radiology – Division of Special and Pediatric Radiology, University Hospital “Umberto I – Lancisi –Salesi”- University Politecnica Marche – Ancona, Italy


gout, dual-energy computed tomography, ultrasonography, imaging, diagnosis, tophaceous gout, non-tophaceous gout


Gout is the most common inflammatory arthritis and is increasing in prevalence and incidence in many countries worldwide. Dual Energy Computed Tomography (DECT) has a high diagnostic accuracy in established gout, but its diagnostic sensitivity is low in subjects with recent-onset gout. A meta-analysis of 17 studies showed a pooled sensitivity and specificity of 0.85 and 0.88, respectively. DECT is a useful diagnostic tool for patients with contraindications for joint aspiration or for those who refuse joint aspiration. This article aims to give an up to date review and summary of existing literature on the role and accuracy of DECT in the imaging of gout.


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How to Cite

Carotti M, Salaffi F, Filippucci E, Aringhieri G, Bruno F, Giovine S, et al. Clinical utility of Dual Energy Computed Tomography in gout: current concepts and applications. Acta Biomed [Internet]. 2020 Jul. 13 [cited 2024 Jul. 23];91(8-S):116-24. Available from: