The Quantitative CT assessment in predicting mortality in patients with Combined Pulmonary Fibrosis and Emphysema and Idiopathic Pulmonary Fibrosis Quantitative CT in combined pulmonary fibrosis and emphysema

Main Article Content

Fatma Üçsular
Gülistan Karadeniz
Gülru Polat
Enver Yalnız
Aysu Ayrancı
Akin Çinkooğlu
Recep Savaş
Hatice Solmaz
Filiz Güldaval
Melih Büyükşirin

Keywords

Combined pulmonary fibrosis and emphysema . idiopathic pulmonary fibrosis . emphysema . quantitative computerized tomography . pulmonary function test

Abstract

Aim: We aimed to evaluate the quantitative CT analysis of patients with CPFE in comparison with IPF and emphysema. Methods: Patients with CPFE(n:36), IPF(n:38) and emphysema(n:32) were retrospectively included in the study with the approval of the ethics committee. Results: There was a positive correlation between total lung volume and FVC%, TLCO% and 6 MWT, and negative correlation between mMRC and mortality. Negative correlation was found between right, left lung density and FVC%, TLCO% and 6 MWT, and positive correlation between mortality. Also, total lung volume, right and left lung densities were significant in predicting mortality and cut-off values ​​are ≤3831,> -778 and> -775, respectively(p = 0.040, 0.020, 0.013). Conclusion: Quantitative CT are guiding in predicting mortality of the disease.

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