Acute eosinophilic pneumonia associated with glyphosate-surfactant exposure

Acute eosinophilic pneumonia associated with glyphosate-surfactant exposure

Authors

  • Wanda M. de Raadt ild care foundation research team, Ede, The Netherlands
  • Petal A. Wijnen 1) ild care foundation research team, Ede, NL; 2) Dept of Clinical Chemistry, Central Diagnostic Laboratory, Maastricht University Medical Centre, Maastricht, NL
  • Aalt Bast Maastricht, University, Faculty of Health, Medicine and Life Sciences, Department of Pharmacology and Toxicology
  • Otto Bekers 2 Dept of Clinical Chemistry, Central Diagnostic Laboratory, Maastricht University Medical Centre, Maastricht, NL
  • Marjolein Drent Maastricht, University, Faculty of Health, Medicine and Life Sciences, Department of Pharmacology and Toxicology

Keywords:

Eosinophilic pneumonia after surfactant exposure

Abstract

We report a case of a female patient who developed acute eosinophilic pneumonia (AEP) after recent onset of smoking and exposure to glyphosate-surfactant.

The additional exposure associated with the recent start of smoking may have contributed to the development and/or severity of AEP.

A clinical relapse after re-challenge four years later both with smoking and glyphosate-surfactant made the association highly likely.

Respiratory distress is a factor of poor outcome and mortality after ingestion of glyphosate-surfactant.

This case highlights the importance of a thorough exposure history e.g., possible occupational and environmental exposures together with drug-intake.

Genotyping should be considered in cases of severe unexplained pulmonary damage

Author Biographies

Wanda M. de Raadt, ild care foundation research team, Ede, The Netherlands

MSc

Petal A. Wijnen, 1) ild care foundation research team, Ede, NL; 2) Dept of Clinical Chemistry, Central Diagnostic Laboratory, Maastricht University Medical Centre, Maastricht, NL

PhD

Aalt Bast, Maastricht, University, Faculty of Health, Medicine and Life Sciences, Department of Pharmacology and Toxicology

Prof. dr.

PhD

Otto Bekers, 2 Dept of Clinical Chemistry, Central Diagnostic Laboratory, Maastricht University Medical Centre, Maastricht, NL

Prof.dr.

PhD

Marjolein Drent, Maastricht, University, Faculty of Health, Medicine and Life Sciences, Department of Pharmacology and Toxicology

Prof.dr.

MD,PhD

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Published

22-07-2015

Issue

Vol. 32 No. 2 (2015)

Section

Letter to Editor

License

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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How to Cite

1.
de Raadt WM, Wijnen PA, Bast A, Bekers O, Drent M. Acute eosinophilic pneumonia associated with glyphosate-surfactant exposure. Sarcoidosis Vasc Diffuse Lung Dis [Internet]. 2015 Jul. 22 [cited 2025 Mar. 15];32(2):172-5. Available from: https://www.mattioli1885journals.com/index.php/sarcoidosis/article/view/4267