Lung placental transmogrification presenting as progressive unilateral interstitial lung disease.

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Agnes Lohbrunner
Laura Bitton
Jacques Remy
Benoit Wallaert
Cecile Chenivesse


transmogrification, interstitial lung disease, emphysema, orphan disease


Placental transmogrification of the lung is an extremely rare lung disease frequently associated with hamartomas or unilateral bullous emphysema. We report a case of placental transmogrification of the lung in a 44-year-old male who presented with bronchial infections, hyperlucent left lung and progressive cystic and micronodular unilateral interstitial lung disease. Because of interstitial lung disease progression over 13 years, a left pneumonectomy was performed. After a two-year follow-up, the patient was asymptomatic and did not exhibit any lung infections. No recurrence was observed on the right lung. 

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