Infection prevention in sarcoidosis: proposal for vaccination and prophylactic therapy

Main Article Content

Huzaefah Syed
Christian Ascoli
Catharina Linssen
Christen Vagts
Thomas Iden
Aamer Syed
Jordana Kron
Kelly Polly
David Perkins
Patricia Finn
Richard Novak
Marjolein Drent
Robert Baughman
Nadera Sweiss

Keywords

Sarcoidosis, infections, opportunistic infections, vaccinations, immunizations, prophylaxis, travel

Abstract

Sarcoidosis is a systemic inflammatory disease characterized by granuloma formation in affected organs and caused by dysregulated immune response to an unknown antigen. Sarcoidosis patients receiving immunosuppressive medications are at increased risk of infection. Lymphopenia is also commonly seen among patient with sarcoidosis. In this review, risk of infections, including opportunistic infections, will be outlined. Recommendations for vaccinations and prophylactic therapy based on literature review will also be summarized.

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