Sars-CoV-2 infection in patients with cystic fibrosis. An overwiew

Sars-CoV-2 infection in patients with cystic fibrosis. An overwiew

Authors

  • Valentina Fainardi Cystic Fibrosis Unit, Children University Hospital, Parma
  • Francesco Longo Department of Medicine and Surgery, Respiratory Disease and Lung Function Unit, University of Parma, Parma, Italy
  • Alfredo Chetta Department of Medicine and Surgery, Respiratory Disease and Lung Function Unit, University of Parma, Parma, Italy.
  • Susanna Esposito Cystic Fibrosis Unit, Children University Hospital, Parma
  • Giovanna Pisi Cystic Fibrosis Unit, Children University Hospital, Parma

Keywords:

SARS-CoV-2, Cystic Fibrosis, Respiratory Viruses

Abstract

The novel coronavirus SARS-CoV-2 was first identified in China in December 2019 and has since spread worldwide. People with Cystic Fibrosis (CF) have reduced survival mainly because of respiratory failure due to chronic pulmonary infections. Therefore, CF patients should be considered to have an increased risk of developing severe manifestations in case of SARS-CoV-2 infection. Surprisingly, the results of recent studies concerning SARS-CoV-2 infection in patients with CF show that in these patients the infection rate was lower than that of the general population. Various factors have been considered to explain a possible protective effect of CF against SARS-CoV-2 infection.

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Published

07-09-2020

Issue

Section

REVIEWS/FOCUS ON - SPECIAL COVID19

How to Cite

1.
Fainardi V, Longo F, Chetta A, Esposito S, Pisi G. Sars-CoV-2 infection in patients with cystic fibrosis. An overwiew . Acta Biomed [Internet]. 2020 Sep. 7 [cited 2024 Oct. 9];91(3):e2020035. Available from: https://www.mattioli1885journals.com/index.php/actabiomedica/article/view/10391