Rehabilitative treatment of patients with COVID-19 infection: the P.A.R.M.A. evidence based clinical practice protocol Covid-19 P.A.R.M.A. Protocol

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Federica Petraglia
Marco Chiavilli
Barbara Zaccaria
Monica Nora
Patrizia Mammi
Elena Ranza
Anais Rampello
Antonio Marcato
Fabio Pessina
Annamaria Salghetti
Cosimo Costantino
Antonio Frizziero
Patrizia Fanzaghi
Silvia Faverzani
Ottavia Bergamini
Stefania Allegri
Francesca Rodà
Rodolfo Brianti
the COVID-19 Rehabilitation Group


covid-19, coronavirus, rehabilitation, clinical protocol


Background: The impact of the SARS-CoV-2 on the National Health System (NHS) required a reorganization of the various levels of care, which also involved the rehabilitation reality.

Aim of the work: A clinical practice review of the literature was conducted to provide operational-rehabilitation guidelines adapted to the local reality and to the recent corporate reorganization in the context of the COVID-19 emergency.

Methods: A practice review of the available scientific evidence was regularly conducted from the start of the COVID-19 pandemic to periodically update the clinical practice guidelines. Articles that met the following inclusion criteria were included: studies conducted on human adult subjects with COVID-19 infection, undergoing rehabilitation in any hospitalization setting.

Results: The results of this clinical practice update were periodically discussed with colleagues and collaborators in a multi-professional team, in order to guarantee a good clinical practice protocol, named P.A.R.M.A.

Conclusions: The P.A.R.M.A. protocol is the result of a periodic review literature update, which has allowed us to take charge of patients affected by COVID-19 according to the most up-to-date clinical evidences, guaranteeing a shared and uniform treatment within a local reality in an era of health emergency.


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