What is the relations between dysgeusia and alterations of the nutritional status? A metanarrative analysis of integrative review

Main Article Content

Federica Dellafiore
Barbara Bascapè
Rosario Caruso
Gianluca Conte
Nathasha Samali Udugampolage
Laura Carenzi
Cristina Arrigoni

Keywords

Malnutrition, obesity, body weight, change in taste, dysgeusia, parageusia

Abstract

Background and aim: Dysgeusia is  an altered or damaged tasting perception of a multifactorial etiology, from polypharmacy, infections to chemotherapy and radiotherapy. Approximately 5% of the population suffer from a diminished taste sensation, which unfortunately remains underestimated by the affected person, creating the conditions for a dramatic underestimation of the incidence of the symptom. The aim of this study is to summarize the evidences present in literature on the relations between Dysgeusia and alterations of the nutritional status


Methods: an integrative review with metanarrative analysis of the articles included was carried out in August 2020. PubMed, Scopus, Embase and CINAHL databases were examined with keywords and methodological strings. PRISMA flow-chart along with a qualitative evaluation grid (JBI-QARI) were applied in the selection of the studies with a time limitation to the last ten years.


Results: 10 articles resulted from the literature review process were divided into two macro-categories. Eight articles reported dysgeusia linked to weight loss. The second macro-category showed two studies relating to dysgeusia in patients with altered nutritional status associated with body weight gain.


Conclusions: this review represents an initial contribution to summarize the best evidence and knowledge in relation to dysgeusia, with the aim of enabling the identification and treatment of this symptom and facilitating targeted educational interventions.

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References

1. Gonella S. L’assistenza al paziente con disturbi del gusto. ZADIG, editor. 2016.
2. Jin S, Lu Q, Jin S, Zhang L, Cui H, Li H. Relationship between subjective taste alteration and weight loss in head and neck cancer patients treated with radiotherapy: A longitudinal study. Eur J Oncol Nurs. 2018;37:43–50.
3. Barasch A, Epstein J. Assessment of taste disorders. Bmj Best Practice 2018 p. 31.
4. Macpherson P. Dysgeusia: a matter of taste and quality of life. Dent Nurs. 2013;9(12):702–5.
5. Piva A, Anzoletti Boscolo A. La disgeusia e la disosmia: disturbi sottovalutati nei pazienti in chemioterapia. L’infermiere. 2016;4:41–5.
6. Speck RM, Demichele A, Farrar JT, Hennessy S, Mao JJ, Stineman MG, et al. Taste alteration in breast cancer patients treated with taxane chemotherapy: Experience, effect, and coping strategies. Support Care Cancer. 2013;21(2):549–55.
7. Le Moigne M, Saint-Jean M, Jirka A, Quéreux G, Peuvrel L, Brocard A, et al. Dysgeusia and weight loss under treatment with vismodegib: benefit of nutritional management. Support Care Cancer. 2016;24(4):1689–95.
8. Chasen M. Long-term oral cancer survivors: disfiguration, taste abnormalities and weight loss. Support Care Cancer. 2011;19(S2):294.
9. Lees J. Incidence of weight loss in head and neck cancer patients on commencing radiotherapy treatment at a regional oncology centre. Eur J Cancer Care (Engl). 1999;8(3):133–6.
10. Greenhalgh T, Robert G, Macfarlane F, Bate P, Kyriakidou O, Peacock R. Storylines of research in diffusion of innovation: a meta-narrative approach to systematic review. Soc Sci Med. 2005 Jul 1;61(2):417–30.
11. Moher D, Liberati A, Tetzlaff J, Altman DG, Group TP. Linee guida per il reporting di revisioni sistematiche e meta-analisi : il PRISMA Statement. Evidence. 2015;7(6).
12. Moola S, Munn Z, Tufanaru C, Aromataris E, Sears K, Sfetcu R, Currie M, Qureshi R, Mattis P, Lisy K MP-F. Checklist for Analytical Cross Sectional Studies. In: M. Z. Aromataris E E, editor. Joanna Briggs Institute Reviewer’s Manual. 2017.
13. Mattes RD , Cowart BJ , Schiavo MA , Arnold C , Garrison B , Kare MR LL. Dietary evaluation of patients with smell and/or taste disorders. Am J Clin Nutr. 1990;51(2):233–40.
14. Markley EJ, Mattes-Kuling DA, Henkin RI. A classification of dysgeusia. J Am Diet Assoc. 1983;83(5):578–80.
15. Pugnaloni S, Vignini A, Borroni F, Sabbatinelli J, Alia S, Fabri M, et al. Modifications of taste sensitivity in cancer patients: a method for the evaluations of dysgeusia. Support Care Cancer. 2019;
16. Mahmoud FA, Aktas A, Walsh D, Hullihen B. A pilot study of taste changes among hospice inpatients with advanced cancer. Am J Hosp Palliat Med. 2011;28(7):487–92.
17. Ferreira MH, Mello Bezinelli L, de Paula Eduardo F, Lopes RM, Pereira AZ, Hamerschlack N, et al. Association of oral toxicity and taste changes during hematopoietic stem cell transplantation: a preliminary study. Support Care Cancer. 2019;
18. Noel CA, Sugrue M, Dando R. Participants with pharmacologically impaired taste function seek out more intense, higher calorie stimuli. Appetite. 2017;117:74–81.
19. Rawal S, Huedo-Medina TB, Hoffman HJ, Swede H, Duffy VB. Structural equation modeling of associations among taste-related risk factors, taste functioning, and adiposity. Obesity. 2017;25(4):781–7.
20. Ackerman D. Nutrition management for the head and neck cancer patient. Cancer Treat Res. 2018;174:174–208.

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