Acute poisoning in children admitted to pediatric emergency department: a five-years retrospective analysis

Acute poisoning in children admitted to pediatric emergency department: a five-years retrospective analysis

Authors

  • Paolo Maurizio Soave Department of Emergency, Anesthesiology and Resuscitation Sciences, Fondazione Policlinico Universitario “A. Gemelli” IRCCS, Rome, Italy
  • Antonietta Curatola Department of Pediatrics, Fondazione Policlinico Universitario “A. Gemelli”, IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy https://orcid.org/0000-0002-2430-9876
  • Serena Ferretti Department of Pediatrics, Fondazione Policlinico Universitario “A. Gemelli”, IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy
  • Vincenzo Raitano Institute of Pediatrics, Università Cattolica del Sacro Cuore, Roma, Italia
  • Giorgio Conti Pediatric Intensive Care Unit, Fondazione Policlinico Universitario “A. Gemelli”, IRCCS, Rome, Italy
  • Antonio Gatto Department of Pediatrics, Fondazione Policlinico Universitario “Agostino Gemelli”, IRCCS, Rome, Italy
  • Antonio Chiaretti a:1:{s:5:"en_US";s:81:"Fondazione Policlinico Gemelli IRCCS - Università Cattolica del Sacro Cuore ROMA";}

Keywords:

children, pediatric, poisoning, toxicology, personalized medicine

Abstract

Background and aim: to identify most frequent risk factors and to propose prevention strategies for the children admitted to Pediatric Emergency Department (PED) with acute poisoning.

Methods: We performed a retrospective study in a tertiary care hospital, describing the frequency and nature of pediatric poisoning, clinical management and outcome.

Results: We collected data of 436 children admitted for acute poisoning. The mean age was 30 months and 51.1% were male. Most poisoning incidents (90.1%) were unintentional and drug ingestion (39.4%) was the leading cause of poisoning. Acute poisoning happened at home in 83,7% of cases and the mother was the most frequent caregiver during the event in 61.5%. No died were reported.

Conclusion: Our study showed that the two categories of patients at greatest risk for acute poisoning are children under 3 years and adolescents over 12 years. Adequate information campaigns about toxic substances are essential for children, adolescents and their parents.

References

1. Kalseen CD, Andur MO, Doull J. Casarett and Doull’s Toxicology. Newyork: Macmillan, 1986
2. Bacha T, Tilahun B. A cross-sectional study of children with acute poisoning: a three-year retrospective analysis. World J Emerg Med. 2015;6:265e9.
3. Woo JH, Ryoo E. Poisoning in Korean children and adolescents. Pediatr Gastroenterol Hepatol Nutr. 2013;16:233e9.
4. Bond GR, Woodward RW, Ho M. The growing impact of pediatric pharmaceutical poisoning. J Pediatr. 2012;160:265e70.
5. Gummin D, Mowry JB, Spyker DA, et al. 2018 Annual Report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 36th Annual Report. Clinical Toxicology 2019; 57: 1220-1413.
6. Hyder AA, Wali S, Fishman S, Schenk E. The burden of unintentional injuries among the under-fi ve population in South Asia. Acta Paediatrica. 2008; 97: 267–275.
7. Peden MK, Sharma G. The Injury Chart Book: A graphical overview of the global burden of injuries. Geneva: World Health Organization, 2002.
8. Rakovcová H. Drug poisoning in children (in Czech). Pediatr praxis. 2013; 14: 126-129
9. Von Mühlendahl Ke, Oberdisse U, Bunjes R, et al. 4 Auflage. Thieme Verlag, Stuttgart, German, 2003, pp 10-75.
10. Bentur Y, Obchinikov Nd, Cahana A, et al. Pediatric poisonings in Israel: National Poison Center data. Isr Med Assoc J. 2010; 12: 554-559
11. Lin YR, Wu TK, Liu TA, et al. Poison exposure and outcome of children admitted to a pediatric emergency department. World J Pediatr. 2011;7:143e9.
12. Mintegi S, Azkunaga B, Prego J, et al. International epidemiological differences in acute poisonings in pediatric emergency departments. Pediatr Emerg Care. 2019; 35:50–57.
13. Mintegi S, Fernández A, Alustiza J, et al. Emergency visits for childhood poisoning: a 2-year prospective multicenter survey in Spain. Pediatr Emerg Care. 2006; 22:334–338.
14. Akin Y, Ağzikuru T, Cömert S, et al. Hospitalizations for pediatric intoxication: a study from Istanbul. Turk J Pediatr. 2011; 53: 369-374
15. Andiran N, Sarikayalar F. Pattern of acute poisonings in childhood in Ankara: what has changed in twenty years? Turk J Pediatr. 2004; 46: 147-152
16. Ouédraogo M, Ouédraogo M, Yéré S, et al. Acute intoxications in two university hospitals in Burkina Faso. Afr Health Sci. 2012; 12: 483-486
17. Zhang Y, Yu B, Wang N, et al. Acute poisoning in Shenyang, China: a retrospective and descriptive study from 2012 to 2016. BMJ Open. 2018;8(8):e021881.
18. Dayasiri MBKC, Jayamanne SF, Jayasinghe CY. Patterns and outcome of acute poisoning among children in rural Sri Lanka. BMC Pediatr. 2018;18(1):274.
19. Manzar N, Saad SM, Manzar B, et al. The study of etiological and demographic characteristics of acute household accidental poisoning in children - a consecutive case series study from Pakistan. BMC Pediatr. 2010; 10, 28
20. Dinis-Oliveira RJ, Magalhães T. Children intoxications: what is abuse and what is not abuse. Trauma Violence Abuse. 2013;14(2):113-132
21. Ramos CL, Barros HM, Stein AT, et al. Risk factors contributing to childhood poisoning. J Pediatr (Rio J). 2010;86(5):435-440
22. Gaw CE, Spiller HA, Casavant MJ, et al. Safety Interventions and Liquid Laundry Detergent Packet Exposures. Pediatrics. 2019;144(1):e20183117.
23. Rodgers GB, Franklin RL, Midgett JD. Unintentional paediatric ingestion poisonings and the role of imitative behaviour. Inj Prev. 2012;18(2):103-108.
24. Agarwal G, Bithu KS, Agarwal R. An epidemiological study of acute poisoning in children in a tertiary care hospital of western Rajasthan, India. Int J Contemp Pediatr. 2016;3:1249e51.
25. Ravindras H, Lavlesh K, Kumar SA, et al. A study of pediatric poisoning cases at district hospital, Belgaum, Karnataka. Medico Legal Update Int J. 2010;10:17e50.
26. Yang CC, Wu JF, Ong HC, et al. Children poisoning in Taiwan. Indian J Pediatr. 1997;64:469e83.
27. Gielen AC, Wilson ME, Faden RR, et al. In-home injury prevention practices for infants and toddlers: the role of parental beliefs, barriers, and housing quality. Health Educ Q. 1995;22:85–95.
28. Mintegi S, Azkunaga B, Prego J, et al. International Epidemiological Differences in Acute Poisonings in Pediatric Emergency Departments. Pediatr Emerg Care. 2019;35(1):50‐57.
29. Burghardt LC, Ayers JW, Brownstein JS, et al. Adult prescription drug use and pediatric medication exposures and poisonings. Pediatrics. 2013; 132: 18-27.

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Published

14-03-2022

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ORIGINAL ARTICLES

How to Cite

1.
Acute poisoning in children admitted to pediatric emergency department: a five-years retrospective analysis. Acta Biomed [Internet]. 2022 Mar. 14 [cited 2024 Jun. 21];93(1):e2022004. Available from: https://www.mattioli1885journals.com/index.php/actabiomedica/article/view/11602