Allergy and COVID-19

Allergy and COVID-19


  • Maria De Filippo Pediatric Unit, Department of Clinical, Surgical, Diagnostic, and Pediatric Sciences, University of Pavia, Pavia, Italy
  • Martina Votto Pediatric Unit, Department of Clinical, Surgical, Diagnostic, and Pediatric Sciences, University of Pavia, Pavia, Italy
  • Ilaria Brambilla Pediatric Clinic, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
  • Riccardo Castagnoli Pediatric Unit, Department of Clinical, Surgical, Diagnostic, and Pediatric Sciences, University of Pavia, Pavia, Italy
  • Lorenza Montagna Pediatric Unit, Department of Clinical, Surgical, Diagnostic, and Pediatric Sciences, University of Pavia, Pavia, Italy
  • Carlo Caffarelli Pediatric Clinic, Department of Medicine and Surgery, Unversity of Parma, Parma, Italy
  • Fabio Cardinale Department of Pediatrics, Giovanni XXIII Pediatric Hospital, University of Bari, Bari, Italy
  • Michele Miraglia Del Giudice 5Department of Woman, Child and of General and Specialized Surgery, University of Campania ‘Luigi Vanvitelli’, Naples, Italy
  • Mariangela Tosca Allergy Centre, IRCCS G. Gaslini Pediatric Hospital, Genova, Italy
  • Silvia Caimmi Pediatric Clinic, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
  • Amelia Licari Clinica Pediatrica, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
  • Gian Luigi Marseglia Pediatric Unit, Department of Clinical, Surgical, Diagnostic, and Pediatric Sciences, University of Pavia, Pavia, Italy


COVID-19, SARS-CoV-2, allergy, allergic asthma, phenotype, eosinophil, children, adolescents


The first cases of as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have been reported in Wuhan, China in December 2019. The World Health Organization declared the global pandemic in March 2020. Coronavirus disease 2019 (COVID-19) showed high rates of mortality in the adult population, whereas a mild course was observed in childhood. Allergic diseases, characterized by a type-2 polarization of the immune system, were considered one of the major risk factor of severe COVID-19. Large amounts of clinical data and expert opinions have been collected since the pandemic outbreak. This review summarizes the latest insights on COVID-19 and allergy.


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How to Cite

Allergy and COVID-19. Acta Biomed [Internet]. 2021 Nov. 29 [cited 2024 Jun. 12];92(S7):e2021522. Available from:

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