Single-dose methotrexate for ectopic pregnancy treatment: preliminary data

Single-dose methotrexate for ectopic pregnancy treatment: preliminary data

Authors

  • C. Merisio
  • S. Anfuso
  • R. Berretta, et al.

Keywords:

MTX, ectopic pregnancy, β-hCG levels

Abstract

Background and aim of the work: our purpose was to evaluate the efficacy of a single-dose of MTX for ectopic pregnancy treatment in a sample of patients carefully selected according to strict inclusion criteria. Methods: 11 patients that matched the inclusion criteria were enrolled. Results: β-hCG at diagnosis averaged 1349 mIU/ml out of the 11 treated patients, 10 (90%) received a single dose of MTX and had a time of EP resolution averaging 27,3 days. The remaining patient received an additional dose of MTX, equal to the start dose, with a time resolution of 35 days. Conclusions: This study provides evidence of the efficacy of MTX in EP treatment, both as therapy and as a form of clinical management: the successful medical management of EP, defined as β-hCG levels becoming negative after administration of one or more MTX doses, was obtained in all treated cases.

Downloads

Published

01-04-2005

Issue

Section

ORIGINAL ARTICLES

How to Cite

1.
Single-dose methotrexate for ectopic pregnancy treatment: preliminary data. Acta Biomed [Internet]. 2005 Apr. 1 [cited 2024 Jun. 20];76(1):33-6. Available from: https://www.mattioli1885journals.com/index.php/actabiomedica/article/view/2021