Hypereosinophilia in a boy with asthma and Varicella Zoster Virus infection

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Margherita Varini
Laura Rinaldi
Lorenza Bonetti
Fabiola Neri
Francesca Santamaria
Giovanna Stringari
Carlo Caffarelli


hypereosinophilia, varicella zoster virus, asthma, children, allergy


Hypereosinophilia is a rare pediatric condition that could be secondary to infections, allergens, immunologic disorders or may be expression of a clonal proliferation. We report the case of an asthmatic boy aged 9 years who presented hypereosinophilia with spontaneous resolution. He had positive serum IgM antibodies to Varicella Zoster Virus while other tests, including genetic ones, gave negative results. Our findings suggest that in children with unexplained hypereosinophilia Varicella Zoster Virus infection should be investigated.


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