In children with Hashimoto’s thyroiditis the evolution over time of thyroid status may differ according to the different presentation patterns

In children with Hashimoto’s thyroiditis the evolution over time of thyroid status may differ according to the different presentation patterns

Authors

  • Giuseppina Zirilli Department of Pediatric, Gynecological, Microbiological and Biomedical Sciences, University of Messina, Messina, Italy
  • Maria Rosa Velletri Department of Pediatric, Gynecological, Microbiological and Biomedical Sciences, University of Messina, Messina, Italy
  • Federica Porcaro Department of Pediatric, Gynecological, Microbiological and Biomedical Sciences, University of Messina, Messina, Italy
  • Gilberto Candela Department of Pediatric, Gynecological, Microbiological and Biomedical Sciences, University of Messina, Messina, Italy
  • Pina Maisano Department of Pediatric, Gynecological, Microbiological and Biomedical Sciences, University of Messina, Messina, Italy
  • Giuseppina La Monica Department of Pediatric, Gynecological, Microbiological and Biomedical Sciences, University of Messina, Messina, Italy

Keywords:

autoimmune thyroid diseases, Down syndrome, euthyroidism, hyperthyroidism, overt hypothy-roidism, subclinical hypothyroidism, Turner syndrome, thyroid function patterns

Abstract

Aim: to report the salient literature news concerning the relationships between thyroid function presenting patterns and subsequent biochemical evolution of Hashimoto’s thyroiditis (HT) in pediatric age. Design: the most recent reports from pediatric literature concerning biochemical thyroid function patterns at HT presentation and their spontaneous changes over time were analyzed and shortly commented. Results: from the analysis of pediatric literature on this theme, it emerges that HT in children may present with a very heterogeneous biochemical picture ranging from overt hypothyroidism to overt hyperthyroidism. The presenting biochemical pattern may also condition its subsequent evolution over time. Conclusions: a) the most common biochemical pattern at HT diagnosis in children is euthyroidism, followed by overt hypothyroidism, subclinical hypothyroidism (SH) and hyperthyroidism; b) the association with HT negatively affects the evolution over time of SH; c) in the cases with either Turner syndrome or Down syndrome the evolution over time of SH is more severe than in those without these chromosomopathies.

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Published

14-09-2015

How to Cite

1.
Zirilli G, Velletri MR, Porcaro F, Candela G, Maisano P, La Monica G. In children with Hashimoto’s thyroiditis the evolution over time of thyroid status may differ according to the different presentation patterns. Acta Biomed [Internet]. 2015 Sep. 14 [cited 2024 Jul. 15];86(2):137-41. Available from: https://www.mattioli1885journals.com/index.php/actabiomedica/article/view/4281