Phenotypic expression of Hashimoto’s thyroiditis is absolutely atypical in girls with Turner syndrome

Phenotypic expression of Hashimoto’s thyroiditis is absolutely atypical in girls with Turner syndrome

Authors

  • Giuseppina Salzano Department of Human Pathology of Adulthood and Childhood, University of Messina, Messina, Italy
  • Mariarosa Calafiore Department of Human Pathology of Adulthood and Childhood, University of Messina, Messina, Italy
  • Cristina Mignosa Department of Human Pathology of Adulthood and Childhood, University of Messina, Messina, Italy
  • Stefano Passanisi Department of Human Pathology of Adulthood and Childhood, University of Messina, Messina, Italy
  • Jessica Trombatore Department of Human Pathology of Adulthood and Childhood, University of Messina, Messina, Italy
  • Giuseppina Zirilli Department of Human Pathology of Adulthood and Childhood, University of Messina, Messina, Italy

Keywords:

autoimmune thyroid disorders, chromosomopathies, epidemiological peculiarities, thyroid function presenting pattern, thyroid function evolution pattern

Abstract

Background: It is unknown whether phenotypic expression of Hashimoto’s thyroiditis (HT) might be conditioned by the association with Turner syndrome (TS). Objectives: To focus on the most recent pediatric studies concerning epidemiology and biochemical course of HT in TS girls. Design: The epidemiological peculiarities of TS-related HT in pediatric age were compared with those usually observed in non-TS girls with HT and results are summarized in Tables 1 and 2. Conclusions: 1) phenotypical expression of HT in TS girls is significantly different from that observed in girls without TS; 2) such differences concern the epidemiological picture, the biochemical presentation modes and also the natural history from HT diagnosis onwards; 3) these peculiarities of TS-related HT are not necessarily linked with a specific karyotype. 

 

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Published

13-09-2016

How to Cite

1.
Salzano G, Calafiore M, Mignosa C, Passanisi S, Trombatore J, Zirilli G. Phenotypic expression of Hashimoto’s thyroiditis is absolutely atypical in girls with Turner syndrome. Acta Biomed [Internet]. 2016 Sep. 13 [cited 2024 Jul. 24];87(2):136-40. Available from: https://www.mattioli1885journals.com/index.php/actabiomedica/article/view/5325