Current trends in etiology, prognosis and therapeutic aspects of Parkinson’s disease: a review

Current trends in etiology, prognosis and therapeutic aspects of Parkinson’s disease: a review

Authors

  • A. J. Jagadeesan
  • R Murugesan
  • S Vimala Devi
  • M. Meera
  • G. Madhumala
  • M. Vishwanathan Padmaja
  • A. Ramesh
  • A. Banerjee
  • S. Sushmitha
  • A. N. Khokhlov
  • F. Marotta
  • Surajit Pathak Dr. Surajit Pathak, M.Sc, Ph.D. Faculty of Allied Health Sciences, Chettinad Hospital & Research Institute (CHRI), Chettinad Academy of Research and Education (CARE), Kelambakkam, Chennai-603103, India Email: [email protected], Phone Number: Off: +91-44-47429050, Cell: 00919002737622, 00919094684087

Keywords:

Parkinson disease, symptom, diagnosis, treatment

Abstract

Parkinson’s disease (PD) is a movement disorder, mainly affecting population consisting of the aged. PD occurs chiefly due to progressive loss of dopaminergic neurons in nigrostriatal pathway. Largely, PD patients suffer from non-motor symptoms, such as depression, anxiety, fatigue, and sleep disorders, that needs further investigation and addressing during PD research. Depression in PD is a predominant and complex symptom, and its pathology exists extrinsic to the nigrostriatal system. This disease can  ultimately be managed by a combination of regular physiotherapy and proper medication. Taking together the present scenario of PD, including the nature of disease, characteristics, treatment, diagnosis of the patients with PD, these outcomes were reviewed to be explored along with many speech-based solutions to PD in this study. This neurodegenerative disorder needs advancement in  research and development which  can help patients with PD to lead a normal life.

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Published

23-10-2017

How to Cite

1.
Jagadeesan AJ, Murugesan R, Vimala Devi S, Meera M, Madhumala G, Vishwanathan Padmaja M, et al. Current trends in etiology, prognosis and therapeutic aspects of Parkinson’s disease: a review. Acta Biomed [Internet]. 2017 Oct. 23 [cited 2024 Jul. 13];88(3):249-62. Available from: https://www.mattioli1885journals.com/index.php/actabiomedica/article/view/6063