Non-invasive method for the assessment of gastric acid secretion

Non-invasive method for the assessment of gastric acid secretion

Authors

  • Chiara Miraglia Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Florenzo Moccia Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Michele Russo Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Serena Scida Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Marilisa Franceschi Endoscopy Unit, Departement of Surgery, ULSS7-Pedemontana, Santorso Hospital, Santorso (VI), Italy
  • Pellegrino Crafa Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Lorella Franzoni Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Antonio Nouvenne Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Tiziana Meschi Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Gioacchino Leandro National Institute of Gastroenterology “S. De Bellis” Research Hospital, Castellana Grotte, Italy
  • Gian Luigi de' Angelis Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Francesco Di Mario Department of Medicine and Surgery, University of Parma, Parma, Italy

Keywords:

acid measurement, atroph, acid secretion, pepsinogens, aspiration test, maximal acid output

Abstract

Methods for the measure of gastric acid secretion include invasive and non-invasive tests. The gold-standard to measure the acid output is the collection of gastric after in basal condition (Basal Acid Output, B.A.O.) and after an i.m. injection of pentagastrin (Maximal Acid Output, M.A.O.). However, direct measurement of gastric acid production is out of order in clinical practice, but many GI symptoms are claimed to be related with acid disorders and empirically cured. Hypochlorhydria is associated with precancerous conditions such as chronic atrophic gastritis (CAG). Acid measurement with non-invasive methods (pepsinogens) is supported by international guidelines.

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Published

17-12-2018

How to Cite

1.
Miraglia C, Moccia F, Russo M, Scida S, Franceschi M, Crafa P, et al. Non-invasive method for the assessment of gastric acid secretion. Acta Biomed [Internet]. 2018 Dec. 17 [cited 2024 Jul. 25];89(8-S):53-7. Available from: https://www.mattioli1885journals.com/index.php/actabiomedica/article/view/7986