Imaging guided percutaneous renal biopsy: do it or not?

Imaging guided percutaneous renal biopsy: do it or not?


  • Francesco Pagnini Department of Medicine and Surgery, Unit of Radiology, University of Parma, Parma, Italy
  • Eleonora Cervi Department of Medicine and Surgery, Unit of Radiology, University of Parma, Parma, Italy
  • Umberto Maestroni Department of Urology, Azienda Ospedaliero-Universitaria di Parma, University of Parma, Parma, Italy
  • Andrea Agostini Department of Clinical, Special and Dental Sciences, University Politecnica delle Marche and Department of Radiology - Division of Special and Pediatric Radiology, University Hospital "Umberto I - Ancona, Italy
  • Alessandra Borgheresi Department of Radiology - Division of Special and Pediatric Radiology, University Hospital "Umberto I - Ancona, Italy
  • Filippo Piacentino Department of Diagnostic and Interventional Radiology, University of Insubria, Ospedale di Circolo e Fondazione Macchi, Varese, Italy
  • Salvatore Alessio Angileri Radiology Department, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, Milan, Italy
  • Anna Maria Ierardi Radiology Department, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, Milan, Italy
  • Chiara Floridi Department of Clinical, Special and Dental Sciences, University Politecnica delle Marche and Department of Radiology - Division of Special and Pediatric Radiology, University Hospital "Umberto I - Ancona, Italy
  • Mattia Carbone Department of Radiology, San Giovanni E Ruggi D'Aragona Hospital, Salerno, Italy
  • Francesco Ziglioli Department of Urology, Azienda Ospedaliero-Universitaria di Parma, University of Parma, Parma, Italy
  • Massimo De Filippo Department of Medicine and Surgery, Unit of Radiology, University of Parma, Parma, Italy


percutaneous renal biopsy, small renal mass, renal cell carcinoma, US-guided biopsy, CT-guided biopsy, coaxial technique.


Since its first reported application, renal biopsy became an important part of the diagnostic algorithm, considered advantages and risks, to better manage therapeutic options. The biopsy can be performed with different techniques (open, laparoscopic, transjugular, transurethral and percutaneous). Currently, the percutaneous approach is the modality of choice. Percutaneous biopsy can be performed under CT or US guidance, but critical benefits and disadvantages have to be considered. Core needle biopsy is usually preferred to fine-needle aspiration because of the sample quality, usually obtaining multiple cores, especially in heterogeneous tumors. Principal complications are hematuria (1-10%), perinephric hematoma (10-90%), pneumothorax (0,6%), clinically significant pain (1,2%).


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Imaging guided percutaneous renal biopsy: do it or not?. Acta Biomed [Internet]. 2020 Jul. 13 [cited 2024 Jun. 21];91(8-S):81-8. Available from:

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