A Descriptive Study of a Turkish Pneumoconiosis Case-Series

Main Article Content

Gülden Sarı
Cebrail Şimşek

Keywords

pneumoconiosis, progressive massive fibrosis, occupational lung disease, sandblasters, ceramic workers, miners, dental technician, foundry workers, pulmonary tuberculosis

Abstract

Background: The study aimed to examine the conditions and factors affecting pneumoconiosis cases to determine the dimensions of the pneumoconiosis problem. Methods: This retrospective study was conducted in a tertiary research hospital between January 1, 2014, and December 31, 2021. Five hundred ninety-seven patients with pneumo- coniosis were included in the study. Results: Large opacities were detected in 157 cases. When we compared cases with and without Pulmonary Massive Fibrosis (PMF), age and concomitant pulmonary disease were higher in PMF cases, which also showed lower FEV1, FVC, and FEV1/FVC. PMF was more frequent in subjects with long dust exposure duration (more than 20 years) and concomitant pulmonary diseases, particularly tuberculosis. Three occupations, sandblasters, dental technicians, and ceramic workers, showed the earliest onset of pneumoconiosis. Conclusions: The study presents pneumoconiosis data in a mixed and large population and contributes to the imple- mentation of evidence-based policies and interventions for countries like Turkey striving to cope with the problem of pneumoconiosis.

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References

REFERENCES
1. Blanc PD, Annesi-Maesano I, Balmes JR, et al. The occupational burden of nonmalignant respiratory dis-eases. An official American Thoracic Society and European Respiratory Society statement. Am J Respir Crit.. 2019;199(11):1312-34.
2. Hoy RF, Chambers DC. Silica‐related diseases in the modern world. Allergy. 2020;75(11):2805-17.
3. James SL, Abate D, Abate KH, et al. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018;392(10159):1789-858.
4. Organization IL. Report of the Working Party on the Definition of Pneumoconiosis. Fourth International Pneumoconiosis Conference; Geneva, Switzerland1971.
5. de Souza Filho AJ, Alice SH. Fibrose maciça pulmonar progressiva. J Bras Pneumol. 1991;17(4):147-53.
6. Santos Ferreira A, Barbosa Moreira V. Progressive massive fibrosis in silica-exposed workers. High-resolution computed tomography findings. J Bras Pneumo. 2006;32(6):523-8.
7. Ng T-P, Chan S-L, Lam K-P. Radiological progression and lung function in silicosis: a ten year follow up study. Br Med J (Clin Res Ed). 1987;295(6591):164-8.
8. Kimura K, Ohtsuka Y, Kaji H, et al. Progression of pneumoconiosis in coal miners after cessation of dust exposure: a longitudinal study based on periodic chest X-ray examinations in Hokkaido, Japan Internal Medicine. 2010;49(18):1949-56.
9. Ng TP, Chan SL. Factors associated with massive fibrosis in silicosis. Thorax. 1991;46(4):229-32.
10. Maclaren W, Hurley J, Collins H, Cowie A. Factors associated with the development of progressive mas-sive fibrosis in British coalminers: a case-control study. Occup Environ Med. 1989;46(9):597-607.
11. Halldin CN, Blackley DJ, Markle T, Cohen RA, Laney AS. Patterns of progressive massive fibrosis on modern coal miner chest radiographs. Arch Environ Occup. 2020;75(3):152-8.
12. McCloskey M, Cook N, Cameron D, Summers Q. Progressive massive fibrosis in the absence of lung mod-ulation. Australas Radiol. 1997;41(1):63-4.
13. Ozmen CA, Nazaroglu H, Yildiz T, et al. MDCT findings of denim-sandblasting-induced silicosis: a cross-sectional study. J Environ Health. 2010;9(1):1-8.
14. Bakan ND, Özkan G, Çamsari G, et al. Silicosis in denim sandblasters. Chest. 2011;140(5):1300-4.
15. Akgun M, Araz O, Ucar EY, et al. Silicosis appears inevitable among former denim sandblasters: a 4-year follow-up study. Chest. 2015;148(3):647-54.
16. Ferreira ÁS, Moreira VB, Ricardo HMV, Coutinho R, Gabetto JM, Marchiori E. Progressive massive fibro-sis in silica-exposed workers: high-resolution computed tomography findings. J Bras Pneumo. 2006;32(6):523-8.
17. Kaya E, Hogg R. In-situ measurements of agglomeration of airborne dust in mines. Emerging Process Technology for a Cleaner Environment SME, Littleton. 1992:259-67.
18. Page SJ, Organiscak JA. Suggestion of a cause-and-effect relationship among coal rank, airborne dust, and incidence of workers’ pneumoconiosis. Aihaj. 2000;61(6):785-7.
19. Becker R, Anderson V, Allen Jr J, Birkhoff R, Ferrell T. Electrical image deposition of charges from lami-nar flow in cylinders. J Aerosol Sci. 1980;11(5-6):461-6.
20. Liao C-M, Wu B-C, Cheng Y-H, You S-H, Lin Y-J, Hsieh N-H. Ceramics manufacturing contributes to ambi-ent silica air pollution and burden of lung disease. Environ Sci Pollut Res. 2015;22(19):15067-79.
21. Cavariani F, Di Pietro A, Miceli M, et al. Incidence of silicosis among ceramic workers in central Italy. Scand J Work Environ. 1995:58-62.
22. Karataş M, GüNdüzöz M, Gökhan O, BAŞeR N. Predictive risk factors for development of silicosis in Turkish ceramic workers. Tuberk Toraks. 2019;67(1):39-46.
23. Morgan WKC, Burgess DB, Lapp NL, Seaton A, Reger RB. Hyperinflation of the lungs in coal miners. Thorax. 1971;26(5):585-90.
24. Yeoh C-I, Yang S-C. Pulmonary function impairment in pneumoconiotic patients with progressive mas-sive fibrosis. Chang Gung Med J. 2002;25(2):72-80.
25. Cowie RL. The epidemiology of tuberculosis in gold miners with silicosis. Am J Respir Crit. 1994;150(5):1460-2.
26. Mosquera J, Rodrigo L, Gonzálvez F. The evolution of pulmonary tuberculosis in coal miners in Asturias, Northern Spain. Eur J Epidemiol. 1994;10(3):291-7.
27. Calvert G, Rice F, Boiano J, Sheehy J, Sanderson W. Occupational silica exposure and risk of various dis-eases: an analysis using death certificates from 27 states of the United States. Occup Environ Med. 2003;60(2):122-9.
28. Bakanlığı TCS. Ulusal_Tuberkuloz_Kontrol_Programi. 2022.
29. Hung C-L, Su P-L, Ou C-Y. Prognostic effect of tuberculosis on patients with occupational lung diseases: A 13-year observational study in a nationwide cohort. Medicine. 2016;95(37).