A mixture of vegetable extracts (chamomile, passionflower, caraway, fennel) and enzymes (beta-galactosidase) for Irritable Bowel Syndrome (IBS): an observational study ("BIOVES") | Progress in Nutrition

Giovanni Tomasello

BIONEC DEPARTMENT, University of Palermo, Italy School of Medicine and Surgery

http://orcid.org/0000-0002-3071-822X
Vincenzo Davide Palumbo

Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy; Department of Surgical, Oncological and Stomatological Disciplines, University of Palermo, Palermo, Italy

Emanuele Sinagra

Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy; 4Digestive Endoscopy Service, “G. Giglio” Hospital, Cefalù, Italy

Margherita Mazzola

Department of Experimental Biomedicine and Clinical Neurosciences, University of Palermo, Palermo, Italy - E-mail: giovanni. tomasello@unipa.it; Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy

Agostino Accardo

School of Medicine, University of Palermo, Palermo, Italy

Andrea Busalacchi

Department of General Surgery and Medical- Surgical Specialties, University of Catania, Catania, Italy

Antonio Ciulla

Torina Hospital, Palermo, Italy

Benedetto Di Trapani

Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy; Torina Hospital, Palermo, Italy

Paolo Pirrotta

Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy

Simone Tomasini

Torina Hospital, Palermo, Italy

Bartolo De Luca

Azienda Sanitaria Provinciale Palermo, Palermo, Italy

Simona Cusimano

Azienda Sanitaria Provinciale Palermo, Palermo, Italy

Salvatore Sardo

Azienda Sanitaria Provinciale Palermo, Palermo, Italy

Giuseppina Di Gaetano

Azienda Sanitaria Provinciale Palermo, Palermo, Italy

Claudia Corallo

Azienda Sanitaria Provinciale Palermo, Palermo, Italy

Gianluca Bonetti

School of Medicine, Poland University, Czech Republic

Monica Pellerone

Kore University, Enna, Italy

Giulia Tomasello

School of Human and Society Sciences, Kore University, Enna, Italy

Provvidenza Damiani

A.O.U.P. “P. Giaccone” Hospital University, Palermo, Italy

Francesco Carini

Department of Experimental Biomedicine and Clinical Neurosciences, University of Palermo, Palermo, Italy

Keywords

irritable bowel syndrome, gastroenterology, alternative treatments

Abstract

Aims: Irritable bowel syndrome (IBS) is a functional intestinal disorder. This syndrome may creates psychological disorders in patients who are affected and severely limits daily activities and lifestyle. Methods: We investigated the effect of the natural product consisting of chamomile, fennel, caraway, passionflower and melissa (Spasmicol®), on IBS patients. For the study, 187 patients with IBS, enrolled by primary care doctors, were treated with Spasmicol® (Aristeia Farmaceutici s.r.l.), two tablets/daily, for 30 days. At the end of the study, patients were re-evaluated to analyse the effects of therapy. Results: After 30 days, patients showed a marked reduction of symptoms (abdominal pain, abdominal distention, stool habit changes). Conclusions: Due to to the combination of chamomile, fennel, caraway, melissa, passionflower and beta-galactosidase, the product Spasmicol® turned out to be remarkedly effective in treating IBS symptoms.

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Published

Sep 23, 2018

DOI https://doi.org/10.23751/pn.v20i3.7574

How to Cite

1.

Tomasello G, Palumbo VD, Sinagra E, Mazzola M, Accardo A, Busalacchi A, Ciulla A, Di Trapani B, Pirrotta P, Tomasini S, De Luca B, Cusimano S, Sardo S, Di Gaetano G, Corallo C, Bonetti G, Pellerone M, Tomasello G, Damiani P, Carini F. A mixture of vegetable extracts (chamomile, passionflower, caraway, fennel) and enzymes (beta-galactosidase) for Irritable Bowel Syndrome (IBS): an observational study ("BIOVES"): STUDIO "BIOVES". Progr Nutr [Internet]. 2018 Sep. 23 [cited 2022 May 19];20(3):526-31. Available from: https://www.mattioli1885journals.com/index.php/progressinnutrition/article/view/7574

Issue

Vol. 20 No. 3 (2018)

Section

Original articles

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Author Biography

Giovanni Tomasello, BIONEC DEPARTMENT, University of Palermo, Italy School of Medicine and Surgery

Professore Aggregato MED 18 Chirurgia Generale, Scuola di Medicina e Chirurgia, Università di Palermo.

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