Giovanni Tomasello
BIONEC DEPARTMENT, University of Palermo, Italy School of Medicine and Surgery
http://orcid.org/0000-0002-3071-822X
Vincenzo Davide Palumbo
Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy; Department of Surgical, Oncological and Stomatological Disciplines, University of Palermo, Palermo, Italy
Emanuele Sinagra
Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy; 4Digestive Endoscopy Service, “G. Giglio” Hospital, Cefalù, Italy
Margherita Mazzola
Department of Experimental Biomedicine and Clinical Neurosciences, University of Palermo, Palermo, Italy - E-mail: giovanni. tomasello@unipa.it; Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy
Agostino Accardo
School of Medicine, University of Palermo, Palermo, Italy
Andrea Busalacchi
Department of General Surgery and Medical- Surgical Specialties, University of Catania, Catania, Italy
Antonio Ciulla
Torina Hospital, Palermo, Italy
Benedetto Di Trapani
Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy; Torina Hospital, Palermo, Italy
Paolo Pirrotta
Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy
Simone Tomasini
Torina Hospital, Palermo, Italy
Bartolo De Luca
Azienda Sanitaria Provinciale Palermo, Palermo, Italy
Simona Cusimano
Azienda Sanitaria Provinciale Palermo, Palermo, Italy
Salvatore Sardo
Azienda Sanitaria Provinciale Palermo, Palermo, Italy
Giuseppina Di Gaetano
Azienda Sanitaria Provinciale Palermo, Palermo, Italy
Claudia Corallo
Azienda Sanitaria Provinciale Palermo, Palermo, Italy
Gianluca Bonetti
School of Medicine, Poland University, Czech Republic
Monica Pellerone
Kore University, Enna, Italy
Giulia Tomasello
School of Human and Society Sciences, Kore University, Enna, Italy
Provvidenza Damiani
A.O.U.P. “P. Giaccone” Hospital University, Palermo, Italy
Francesco Carini
Department of Experimental Biomedicine and Clinical Neurosciences, University of Palermo, Palermo, Italy
Keywords
irritable bowel syndrome, gastroenterology, alternative treatments
Abstract
Aims: Irritable bowel syndrome (IBS) is a functional intestinal disorder. This syndrome may creates psychological disorders in patients who are affected and severely limits daily activities and lifestyle. Methods: We investigated the effect of the natural product consisting of chamomile, fennel, caraway, passionflower and melissa (Spasmicol®), on IBS patients. For the study, 187 patients with IBS, enrolled by primary care doctors, were treated with Spasmicol® (Aristeia Farmaceutici s.r.l.), two tablets/daily, for 30 days. At the end of the study, patients were re-evaluated to analyse the effects of therapy. Results: After 30 days, patients showed a marked reduction of symptoms (abdominal pain, abdominal distention, stool habit changes). Conclusions: Due to to the combination of chamomile, fennel, caraway, melissa, passionflower and beta-galactosidase, the product Spasmicol® turned out to be remarkedly effective in treating IBS symptoms.