Factors influencing quality of life in cancer patients receiving haemodialysis

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Kadir Gokhan Atilgan https://orcid.org/0000-0001-9905-4305
Mehmet Deniz Ayli https://orcid.org/0000-0003-3145-1595
Tulay Eren https://orcid.org/0000-0002-0088-1149
Cengiz Karacin https://orcid.org/0000-0002-7310-9328
Hatice Sahin https://orcid.org/0000-0002-7146-4828
Tamer Selen https://orcid.org/0000-0003-2617-2372
Ebru Gok Oguz
Fatma Ayerden Ebinc https://orcid.org/0000-0002-7893-3498
Gulay Ulusal Okyay https://orcid.org/0000-0003-0770-1283


cancer, hand grip strength, haemodialysis, inflammation, malnutrition, physical activity, quality of life


Background: Life expectancy in cancer patients is shorter than in the general population. Therefore
quality of life is important. The quality of life and the affecting factors in cancer patients receiving haemodialysis
(HD) treatment are not clearly known. Objective: This study evaluated factors affecting quality of life in cancer
patients undergoing HD compared to patients without cancer undergoing HD. Methods: The study was conducted between May 2019 and September 2019. The dialysis unit of the authors’ hospital and ten private HD
centres participated in the present case control study. The study included 37 cancer patients undergoing HD
(Group CA) and age, sex matched 37 patients undergoing HD without cancer (Group C). Quality of life was
assessed with the health-related quality of life short form-36. Muscle mass and malnutrition were evaluated with the hand grip strength (HGS) test and malnutrition-inflammation score (MIS). Sleep disorder was assessed
using the Pittsburgh sleep quality index (PSQI). Results: In Group CA, HGS was significantly related to both
mental composite scores and mental health (p = 0.023, r = 0.374; p < 0.001, r = 0.519, respectively). In Group C,
a significant relationship was detected between HGS and both physical composite scores and general health (p
= 0.03, r = 0.356; p = 0.017, r = 0.397, respectively), between the PSQI and physical role functioning (p = 0.03, r
= -0.336) and between the MIS and HGS (p = 0.012, r = -0.408). Conclusion: Only HGS affected quality of life
in cancer patients undergoing receiving HD treatment.


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