Clinical efficacy, safety and tolerability of BIO-C® (micronizedSilymarin) as a galactagogue

Clinical efficacy, safety and tolerability of BIO-C® (micronizedSilymarin) as a galactagogue

Authors

  • F. Di Pierro
  • A. Callegari
  • D. Carotenuto
  • M. M. Tapia

Keywords:

Silymarin, galactagogue, BIO-C®

Abstract

Background and aim of the work: The authors have previously reported the use of Silymarin (a Silybum marianum standardized extract) as a promoter of milk production in cows. Due to the important psychological impact of hypogalactia in women after delivery, we evaluated the role of Silymarin as a safe and effective galactogogue for human species. Methods: 50 healthy women during lactation were enrolled in order to verify the galactogogue role played by an oral treatment with micronized Silymarin (420 mg/day) in comparison with an undistinguishable placebo product. Results: Women orally treated for 63 days with Silymarin showed a clear galactagogue role for the product with an increase of 85.94% of the daily milk production (placebo: +32.09%). No drop out, nor unwanted effects were reported in both groups. Compliance and tolerability were also very good. Conclusions: Silymarin may be considered as a safe and effective herbal product that can be orally administered in order to improve the daily milk production in healthy women after delivery, without affecting milk quality.

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Published

01-12-2008

Issue

Section

ORIGINAL ARTICLES

How to Cite

1.
Clinical efficacy, safety and tolerability of BIO-C® (micronizedSilymarin) as a galactagogue. Acta Biomed [Internet]. 2008 Dec. 1 [cited 2024 Jun. 23];79(3):205-10. Available from: https://www.mattioli1885journals.com/index.php/actabiomedica/article/view/1249