Surfactant administration in spontaneous breathing with N-CPAP for RDS

Surfactant administration in spontaneous breathing with N-CPAP for RDS

Authors

  • G. Lista “V. Buzzi” Ospedale dei Bambini Azienda ICP, Milano (Italy)
  • F. Castoldi

Keywords:

surfactant, spontaneous breathing, preterm infants, RDS

Abstract

Surfactant administration in spontaneous breathing with N-CPAP seems to be a promising approach in the management of neonatal RDS. Both recent RCTs and single centre experience have shown feasibility and good respiratory outcomes with this approach even in extremely preterm infants with respiratory failure. The results of these studies seem to demonstrate that avoiding mechanical ventilation and manual inflation (therefore the risk of high positive pressure and inappropriate tidal volume) it is possible to reduce the risk of VILI and the evolution towards BPD. Further large clinical studies are needed to confirm this hypothesis.

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Published

20-06-2014

Issue

Section

ORIGINAL ARTICLES

How to Cite

1.
Lista G, Castoldi F. Surfactant administration in spontaneous breathing with N-CPAP for RDS. Acta Biomed [Internet]. 2014 Jun. 20 [cited 2024 Jul. 12];85(1):35-8. Available from: https://www.mattioli1885journals.com/index.php/actabiomedica/article/view/3688